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ProSci Inc.
Numéro de catalogue:
(PRSI25-726)
Fournisseur:
ProSci Inc.
Description:
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta (5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-721)
Fournisseur:
ProSci Inc.
Description:
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life.Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-728)
Fournisseur:
ProSci Inc.
Description:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been found for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5267P)
Fournisseur:
ProSci Inc.
Description:
CIP75 peptide is used for blocking the activity of CIP75 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5275P)
Fournisseur:
ProSci Inc.
Description:
PALB2 peptide is used for blocking the activity of PALB2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5627P)
Fournisseur:
ProSci Inc.
Description:
BCAS2 pepide is used for blocking the activity of BCAS2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5305)
Fournisseur:
ProSci Inc.
Description:
TWA1 Antibody: TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5303)
Fournisseur:
ProSci Inc.
Description:
ABIN3 Antibody: The nuclear factor NF-kappa B plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kappa B activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kappa B activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kappa B activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kappa B inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kappa B in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-309)
Fournisseur:
ProSci Inc.
Description:
SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. SSB protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.La is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU (OH) elements of newly RNA polymerase III (see MIM 606007)-transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. La protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome (MIM 270150) and systemic lupus erythematosus (SLE; MIM 152700) (Teplova et al., 2006).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-663)
Fournisseur:
ProSci Inc.
Description:
Anti-GDF15 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-653)
Fournisseur:
ProSci Inc.
Description:
Anti-GALR1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-671)
Fournisseur:
ProSci Inc.
Description:
Anti-GIPC3 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-665)
Fournisseur:
ProSci Inc.
Description:
Anti-GSN Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-903)
Fournisseur:
ProSci Inc.
Description:
Claudin 6 Plays a major role in tight junction-specific obliteration of the intercellular space. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO- 3.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-928)
Fournisseur:
ProSci Inc.
Description:
YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-936)
Fournisseur:
ProSci Inc.
Description:
Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion
UOM:
1 * 1 EA
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