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ProSci Inc.
Numéro de catalogue:
(PRSI29-485)
Fournisseur:
ProSci Inc.
Description:
LARP1 belongs to the LARP family and it contains 1 HTH La-type RNA-binding domain. The exact function of LARP1 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-171)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin Carboxyl-Terminal Hydrolase 14 (USP14) belongs to the ubiquitin-specific processing (USP) family which is a deubiquitinating enzyme (DUB) with His and Cys domains. USP14 located in the cytoplasm is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. USP14 acts also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. In addition, USP14 is indispensable for synaptic development and function at neuromuscular junctions, required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-688)
Fournisseur:
ProSci Inc.
Description:
ZFP92 belongs to the krueppel C2H2-type zinc-finger protein family. It contains 8 C2H2-type zinc fingers and 1 KRAB domain. ZFP92 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI30-675)
Fournisseur:
ProSci Inc.
Description:
The exact function of LOC728566 remains unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI42-627)
Fournisseur:
ProSci Inc.
Description:
Anti-GRM2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-113)
Fournisseur:
ProSci Inc.
Description:
Anti-PITPNA Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI35-463)
Fournisseur:
ProSci Inc.
Description:
Anti-Influenza Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-508)
Fournisseur:
ProSci Inc.
Description:
RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-934)
Fournisseur:
ProSci Inc.
Description:
Glutamate dehydrogenase (EC 1.4.1.3) catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate using NAD and/or NADP as cofactors.Glutamate dehydrogenase (EC 1.4.1.3) catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate using NAD and/or NADP as cofactors. See also GLUD1 (MIM 138130).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4001P)
Fournisseur:
ProSci Inc.
Description:
APH1 peptide is used for blocking the activity of APH1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-119)
Fournisseur:
ProSci Inc.
Description:
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5163P)
Fournisseur:
ProSci Inc.
Description:
LDL-R peptide is used for blocking the activity of LDL-R antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4817)
Fournisseur:
ProSci Inc.
Description:
ZBRK1 Antibody: ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator with tumor suppressor activity. ZBRK1 binds to a specific sequence within the GADD45 gene, supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription. Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD), and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements. These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4813)
Fournisseur:
ProSci Inc.
Description:
CNOT4 Antibody: CNOT4 is a component of the CCR4-NOT transcription complex, a complex that is implicated in the repression of RNA polymerase II transcription. In the CCR4-NOT complex, CNOT4 acts as an E3 ubiquitin-protein ligase and interacts with a subset of E2 ubiquitin-conjugating enzymes through a unique C4C4 RING domain. This E3 ligase activity was shown to be dependent on the selective and specific interaction with the ubiquitin conjugating enzyme UbcH5B. In yeast, mutations in CNOT4 that prevented its interaction with the UbcH5B homolog UBC4 caused increased sensitivity to hydroxyurea, heat shock, and hygromycin B, suggesting that CNOT4 and UbcH5B are involved in stress response in vivo. Multiple isoforms of CNOT4 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI25-658)
Fournisseur:
ProSci Inc.
Description:
DGCR8 contains 2 DRBM (double-stranded RNA-binding) domains and 1 WW domain. It may play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-661)
Fournisseur:
ProSci Inc.
Description:
RBM35B contains 3 RRM (RNA recognition motif) domains. ESRP1 and ESRP2 (RBM35B) are epithelial cell-type-specific regulators of FGFR2 splicing.
UOM:
1 * 50 µG
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