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ProSci Inc.


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Numéro de catalogue: (PRSI29-927)

Fournisseur:  ProSci Inc.
Description:   SLC43A3 belongs to the SLC43A transporter family and is a putative transporter.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI91-069)

Fournisseur:  ProSci Inc.
Description:   Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI46-650)

Fournisseur:  ProSci Inc.
Description:   Anti-DACH2 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI46-653)

Fournisseur:  ProSci Inc.
Description:   Anti-ENOX2 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI46-646)

Fournisseur:  ProSci Inc.
Description:   Anti-CLPB Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI49-111)

Fournisseur:  ProSci Inc.
Description:   Anti-MAP2 Mouse Monoclonal Antibody
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI46-672)

Fournisseur:  ProSci Inc.
Description:   Anti-HRASLS Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI3881P)

Fournisseur:  ProSci Inc.
Description:   TIP47 peptide is used for blocking the activity of TIP47 antibody.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI3863P)

Fournisseur:  ProSci Inc.
Description:   UNG1 peptide is used for blocking the activity of UNG1 antibody.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI7381)

Fournisseur:  ProSci Inc.
Description:   N-RAS Antibody: Activating mutations and overexpression of classical Ras subfamily members (N-RAS, H-RAS, and K-RAS) have been widely investigated as key events in the development of human cancers. The N-RAS protein shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. N-RAS, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI7391)

Fournisseur:  ProSci Inc.
Description:   AKT1S1 Antibody: The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can indusce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI7389)

Fournisseur:  ProSci Inc.
Description:   DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma. DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI5683)

Fournisseur:  ProSci Inc.
Description:   TMEM184B Antibody: TMEM184B, also known as C22orf5, is a 407 amino acid multi-pass membrane protein and represents a novel gene in the activation of the MAPK signaling pathway. The gene encoding TMEM184B maps to human chromosome 22; mutations in several of the genes in chromosome 22 are involved in the development of autism, schizophrenia, Phelan-McDermid syndrome and Neurofibromatosis type 2, suggesting that TMEM184B may play a role in these syndromes.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI28-746)

Fournisseur:  ProSci Inc.
Description:   ZNF441 contains 19 C2H2-type zinc fingers and belongs to the krueppel C2H2-type zinc-finger protein family. It may be involved in transcriptional regulation.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI28-735)

Fournisseur:  ProSci Inc.
Description:   MED21 belongs to the Mediator complex subunit 21 family. It is the component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI7187)

Fournisseur:  ProSci Inc.
Description:   FOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
UOM:  1 * 1 EA
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