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ProSci Inc.


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Numéro de catalogue: (PRSI28-310)

Fournisseur:  ProSci Inc.
Description:   Human ADP-ribose pyrophosphatase NUDT9 belongs to a superfamily of Nudix hydrolases that catabolize potentially toxic compounds in the cell. NUDT9 alpha protein is targeted highly specifically to mitochondria, whereas the predicted protein of the NUDT9 beta transcript, which is missing this sequence, exhibits no clear subcellular localization. Investigation of the physical and enzymatic properties of NUDT9 indicates that it is functional as a monomer, optimally active at near neutral pH, and that it requires divalent metal ions and an intact Nudix motif for enzymatic activity.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI28-317)

Fournisseur:  ProSci Inc.
Description:   CACNB2 is a member of the ion-channel gene superfamily. Described as a Lambert-Eaton myasthenic syndrome (LEMS) antigen in humans, this gene is found close to a region that undergoes chromosome rearrangements in small cell lung cancer, which occurs in association with LEMS.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI90-333)

Fournisseur:  ProSci Inc.
Description:   DLK1 (Protein delta homolog 1; Preadipocyte factor 1; Pref-1) is a regulator of adipocyte differentiation found in serum and urine. DLK1 might be a decoy ligand. Serum or plasma levels of soluble DLK1 affect negatively or positively adipogenesis and control mesenchymal cell fate. DLK1 is frequently upregulated in myelodysplastic syndrome (MDS) patients compared to non-leukemic individuals.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI25-635)

Fournisseur:  ProSci Inc.
Description:   BCAS2 belongs to the SPF27 family. It is involved in mRNA splicing. The protein might play an important role in breast cancer development by increasing the estrogen receptor's function.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI3217P)

Fournisseur:  ProSci Inc.
Description:   ACE2 peptide is used for blocking the activity of ACE2 antibody.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-912)

Fournisseur:  ProSci Inc.
Description:   SLC7A1 is a high-affinity, low capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) in non-hepatic tissues. It may also function as an ecotropic retroviral leukemia receptor.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI45-679)

Fournisseur:  ProSci Inc.
Description:   Anti-GRIK1 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI46-879)

Fournisseur:  ProSci Inc.
Description:   Anti-NOTCH1B Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI46-843)

Fournisseur:  ProSci Inc.
Description:   Anti-FOXI2 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI46-842)

Fournisseur:  ProSci Inc.
Description:   Anti-FMR1 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSIXP-5240)

Fournisseur:  ProSci Inc.
Description:   Anti-CCL20 Rabbit Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSIXP-5240BT)

Fournisseur:  ProSci Inc.
Description:   Anti-CCL20 Rabbit Polyclonal Antibody (Biotin)
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI4595)

Fournisseur:  ProSci Inc.
Description:   VPS53 Antibody: The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI4597)

Fournisseur:  ProSci Inc.
Description:   TNPO3 Antibody: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI4615)

Fournisseur:  ProSci Inc.
Description:   UROP11 Antibody: Upregulated obese product 11 (UROP11) was isolated from subtractive library for mouse hypothalamus. It is detected in numerous tissues and is upregulated in the hypothalamus and adipocytes in obese mice. UROP11 is also observed in human neural and lymphoid tissues; its expression appears to be regulated by the level of lymphoid activation. Urop11 expression is strongly upregulated both in vivo in mouse hypothalamus and in vitro in mouse neural cell lines after treatment with leptin, indicating Urop11 is a target of leptin activity and thus may play a role in obesity.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI4609)

Fournisseur:  ProSci Inc.
Description:   Rim2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. Rim1 and Rim2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release; synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like Rim1, Rim 2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner. Rim2 is known to exist in multiple isoforms; this antibody should recognize most of them.
UOM:  1 * 1 EA
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