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ProSci Inc.
Numéro de catalogue:
(PRSI25-315)
Fournisseur:
ProSci Inc.
Description:
ZBTB10 contains 1 BTB (POZ) domain and 2 C2H2-type zinc fingers. ZBTB10 may be involved in transcriptional regulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI70-672)
Fournisseur:
ProSci Inc.
Description:
Anti-RHOH Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Numéro de catalogue:
(PRSI70-060)
Fournisseur:
ProSci Inc.
Description:
Anti-CK7 Mouse Monoclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI70-778)
Fournisseur:
ProSci Inc.
Description:
Anti-MCL1 Rabbit Polyclonal Antibody
UOM:
1 * 250 µl
Numéro de catalogue:
(PRSI70-749)
Fournisseur:
ProSci Inc.
Description:
Anti-SYK Rabbit Polyclonal Antibody
UOM:
1 * 250 µl
Numéro de catalogue:
(PRSI70-741)
Fournisseur:
ProSci Inc.
Description:
Anti-CLDN11 Rabbit Polyclonal Antibody
UOM:
1 * 250 µl
Numéro de catalogue:
(PRSI28-772)
Fournisseur:
ProSci Inc.
Description:
ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI28-778)
Fournisseur:
ProSci Inc.
Description:
GTF2H4 belongs to the TFB2 family. It is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5043)
Fournisseur:
ProSci Inc.
Description:
TMEM18 Antibody: Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-765)
Fournisseur:
ProSci Inc.
Description:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-764)
Fournisseur:
ProSci Inc.
Description:
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-κ-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7522)
Fournisseur:
ProSci Inc.
Description:
Regulator of G protein signalling 12 , RGS12, domain aa 1372-1447. This protein negatively regulates G protein-coupled receptor signalling.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-771)
Fournisseur:
ProSci Inc.
Description:
May associate with CD21. May regulate the release of Ca2+ from intracellular stores.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-766)
Fournisseur:
ProSci Inc.
Description:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI31-025)
Fournisseur:
ProSci Inc.
Description:
The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI31-034)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by CDC2 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
UOM:
1 * 50 µG
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