ProSci Inc.
Numéro de catalogue:
(PRSI79-619)
Fournisseur:
ProSci Inc.
Description:
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC gamma1.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-623)
Fournisseur:
ProSci Inc.
Description:
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-610)
Fournisseur:
ProSci Inc.
Description:
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-603)
Fournisseur:
ProSci Inc.
Description:
May be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-622)
Fournisseur:
ProSci Inc.
Description:
a maternal imprinting gene. May possess growth suppressor activity. Two major alternatively spliced isoforms have been described. forms. One form, Meg3-proximal (Meg3p), contains exons 1-3. The second form, Meg3-distal (Meg3d) did not contain exons 1-3 and was present in oocytes and in 1- and 2-cell embryos
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXG-6156)
Fournisseur:
ProSci Inc.
Description:
Anti-CXADR Chicken Polyclonal Antibody
UOM:
1 * 500 µG
Numéro de catalogue:
(PRSIXG-6174)
Fournisseur:
ProSci Inc.
Description:
Anti-FABP4 Chicken Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSIXG-6165)
Fournisseur:
ProSci Inc.
Description:
Anti-KCNE2 Chicken Polyclonal Antibody
UOM:
1 * 500 µG
Numéro de catalogue:
(PRSIXG-6175)
Fournisseur:
ProSci Inc.
Description:
Anti-CRP Chicken Polyclonal Antibody
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI79-618)
Fournisseur:
ProSci Inc.
Description:
Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5359)
Fournisseur:
ProSci Inc.
Description:
Swine H1N1 Nonstructural Protein 1 Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2'-5'OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the anti-viral protein kinase PKR.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5383)
Fournisseur:
ProSci Inc.
Description:
JMJD6 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. JMJD6 was initially identified as a membrane protein that participates in phagocytosis but recent studies have shown that it has other functions when it is expressed in the cytosol and nucleus. JMJD6 is thought to play important roles in regulation of development and differentiation as knockdown experiments in mice resulted in neonatal lethality with severe defects in the morphology of numerous organs. JMJD6 also can catalyze the lysyl-hydroxylation of U2AF65, a protein involved with RNA splicing, suggesting that some of the functions attributed to JMJD6 may be due to its regulatory activity of RNA splicing.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5379)
Fournisseur:
ProSci Inc.
Description:
JMJD4 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. While several JMJD proteins have been identified as being involved in chromatin regulation, histone demethylation and development, the JMJD4 has not been identified. JMJD4 is expressed in multiple tissues and At least three isoforms of JMJD4 are known to exist.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI5361)
Fournisseur:
ProSci Inc.
Description:
Seasonal H1N1 Nucleocapsid Protein Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus (S-OIV) was identified in specimens obtained from patients in Mexico and the United States. The influenza A virus polymerase transcribes and replicates eight virion RNA (vRNA) segments, among which the nucleocapsid protein (NP), thought to control whether mRNA or cRNA is produced. The nucleoprotein (NP), which has multiple functions during the virus life cycle, possesses regions that are highly conserved among influenza A, B, and C viruses. It was recently found several NP mutations that affected the efficient incorporation of multiple viral-RNA (vRNA) segments into progeny virions even though a single vRNA segment was incorporated efficiently. This indicates that the respective conserved amino acids in NP may be critical for the assembly and/or incorporation of sets of eight vRNA segments.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-858)
Fournisseur:
ProSci Inc.
Description:
NPAL2 is a multi-pass membrane protein and it belongs to the NIPA family. The exact function of NPAL2 remains unknown.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-431)
Fournisseur:
ProSci Inc.
Description:
MKX is a member of the TALE superclass of atypical homeobox genes that is most closely related to the Iroquois class.
UOM:
1 * 50 µG
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