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Protéines et Peptides
Numéro de catalogue:
(PRSI91-805)
Fournisseur:
ProSci Inc.
Description:
LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-383)
Fournisseur:
ProSci Inc.
Description:
Secretogranin-3(SCG3) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. SCG3 is expressed in brain, heart, kidney, liver and skeletal muscle. It may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5369P)
Fournisseur:
ProSci Inc.
Description:
JMJD1B peptide is used for blocking the activity of JMJD1B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5375P)
Fournisseur:
ProSci Inc.
Description:
JMJD2B peptide is used for blocking the activity of JMJD2B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-093)
Fournisseur:
ProSci Inc.
Description:
Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF expression levels are high in the nucleus and cytoplasm of smooth muscle and endothelial cells. HDGF has proliferative, angiogenic and neurotrophic activity. HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. As a heparin-binding protein, which is highly expressed in tumor cells where it stimulates proliferation. HDGF has mitogenic activity for fibroblasts and acts as a transcriptional repressor. It has been shown that HDGF is linked with tumorigenesis and the growth of cancer.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-082)
Fournisseur:
ProSci Inc.
Description:
Programmed Cell Death Protein 10 (PDCD10) belongs to the PDCD10 family. PDCD10 exists as a homodimer and is widely expressed. PDCD10 can increase mitogen-activated protein kinase activity and MST4 activity. PDCD10 is required for normal cardiovascular development and normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Defects in PDCD10 are the cause of cerebral cavernous malformations type 3.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4043P)
Fournisseur:
ProSci Inc.
Description:
SCO1 peptide is used for blocking the activity of SCO1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3357P)
Fournisseur:
ProSci Inc.
Description:
BOK peptide is used for blocking the activity of BOK antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7227P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the center of human CCL4.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-689)
Fournisseur:
ProSci Inc.
Description:
Sonic hedgehog protein (SHH) is also known as HHG-1, which belongs to the hedgehog family. SHH is expressed in fetal intestine, liver, lung, and kidney and not expressed in adult tissues. Sonic hedgehog protein can be cleavage into sonic hedgehog protein N-product and sonic hedgehog protein C-product by autolysis. SHH binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development. The C-terminal domain displays an autoproteolysis activity and a cholesterol transferase activity. The N-product is the active species in both local and long-range signaling, whereas the C-product has no signaling activity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5497P)
Fournisseur:
ProSci Inc.
Description:
CLPH peptide is used for blocking the activity of CLPH antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-171)
Fournisseur:
ProSci Inc.
Description:
Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumour growth, and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signalling molecule in the induction and patterning of the embryonic brain. In addition, FGF17 stimulates the proliferation and activation of cells that express FGF receptors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5253P)
Fournisseur:
ProSci Inc.
Description:
EphA10 peptide is used for blocking the activity of EphA10 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-461)
Fournisseur:
ProSci Inc.
Description:
Interleukin-1 beta (IL-1β) is also known as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene. IL-1β precursor is cleaved by caspase 1 (interleukin 1 beta convertase). Cytosolic thiol protease cleaves the product to form mature IL-1 beta.
IL1β are structurally related polypeptides that share approximately 21% amino acid (aa) identity in human. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL1α and IL1β are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1β is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
UOM:
1 * 20 µG
Numéro de catalogue:
(PRSI92-066)
Fournisseur:
ProSci Inc.
Description:
D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial (BDH) is a member of the short-chain dehydrogenases/reductases (SDR) family. BDH is localized in the mitochondrion matrix. BDH forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific necessity for phosphatidylcholine for optimal enzymatic activity. BDH catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the 2 main ketone bodies formed during fatty acid catabolism.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-067)
Fournisseur:
ProSci Inc.
Description:
Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.
UOM:
1 * 50 µG
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