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Protéines et Peptides
Numéro de catalogue:
(PRSI4645P)
Fournisseur:
ProSci Inc.
Description:
Nanos2 peptide is used for blocking the activity of Nanos2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5169P)
Fournisseur:
ProSci Inc.
Description:
ST3gal6 peptide is used for blocking the activity of ST3gal6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5155P)
Fournisseur:
ProSci Inc.
Description:
beta-Galactosidase peptide is used for blocking the activity of b-galactosidase antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-085)
Fournisseur:
ProSci Inc.
Description:
Signal Transducer and Activator of Transcription 3 (STAT3) belongs to the transcription factor STAT family. STAT3 contains one SH2 domain and is a transcription factor expressed in most cell types. STAT3 is activated by multiple cytokines and growth factors including: IFN-a, IL-10, IL-6, IL-11, IL-12, IL-2, EGF etc. STAT3 functions as signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. In addition, STAT3 may also mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-076)
Fournisseur:
ProSci Inc.
Description:
Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on the cell membrane and occasionally in the cytoplasm of tumor cells in 97% of samples from patients with hairy cell leukemia.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-070)
Fournisseur:
ProSci Inc.
Description:
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-035)
Fournisseur:
ProSci Inc.
Description:
Interleukin-16 (IL-16) is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils. Analysis by gel filtration suggests that, under physiological conditions, human IL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4+ T cells. Human and murine IL-16 show significant cross-species reactivity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-705)
Fournisseur:
ProSci Inc.
Description:
Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumour cells from apoptosis. It is commonly used as a cancer marker.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5119P)
Fournisseur:
ProSci Inc.
Description:
Norrin peptide is used for blocking the activity of Norrin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5121P)
Fournisseur:
ProSci Inc.
Description:
ZBED2 peptide is used for blocking the activity of ZBED2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5123P)
Fournisseur:
ProSci Inc.
Description:
ZBED3 peptide is used for blocking the activity of ZBED3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-078)
Fournisseur:
ProSci Inc.
Description:
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-050)
Fournisseur:
ProSci Inc.
Description:
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-046)
Fournisseur:
ProSci Inc.
Description:
Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2383P)
Fournisseur:
ProSci Inc.
Description:
p53R2 peptide is used for blocking the activity of p53R2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2347P)
Fournisseur:
ProSci Inc.
Description:
DC-SIGN peptide is used for blocking the activity of DC-SIGN antibody.
UOM:
1 * 50 µG
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