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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI56-700)
Fournisseur:
ProSci Inc.
Description:
PIK3AP1 is involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI6383)
Fournisseur:
ProSci Inc.
Description:
TEKT5 Antibody: Tektins are insoluble alpha-helical proteins related to intermediate filament proteins and are essential for the assembly of cilia and flagella. Tektin-5 (TEKT5) is a recently identified member of the Tektin family. It is predominantly expressed in testis, and its expression is upregulated during testis development. It is present in sperm flagella but not in heads, suggesting that it may act as a middle component required for flagellar stability and sperm mobility.
UOM:
1 * 1 EA
Numéro de catalogue:
(STMC100-1394)
Fournisseur:
STEMCELL Technologies
Description:
Stimulating T cells with HPV16 (E7) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HPV16 (E7) Peptide pool is a lyophilised mixture of 22 peptides from protein E7 of human papillomavirus type 16 (HPV16) consisting of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 98 on protein E7. E7 is an oncoprotein that binds and mediates degradation of the retinoblastoma tumor suppressor protein pRB (Gonzalez <i>et al.</i>). E7 together with E6 demonstrated the ability to immortalize human keratinocytes in vitro, which likely has significance for HPVs oncogenic potential (Hawley-Nelson <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
UOM:
1 * 1 PE
New Product
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(PRSI79-868)
Fournisseur:
ProSci Inc.
Description:
Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-257)
Fournisseur:
ProSci Inc.
Description:
RARA contains 1 nuclear receptor DNA-binding domain and belongs to the nuclear hormone receptor family, NR1 subfamily. It is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-461)
Fournisseur:
ProSci Inc.
Description:
ESX1 is a homeobox gene related to the mouse Esx1 homeobox gene. ESX1 is expressed during all stages of placental development and is localized to sparse areas of trophoblast in terminal villi in association with cytotrophoblastic cells. Proteolytic processing of ESX1 plays a role in concerted regulation of the cell cycle and transcription in human cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(AGRIAS224879)
Fournisseur:
Agrisera
Description:
OPT3 (Oligopeptide transporter 3) is a phloem-specific iron transporter that is essential for systemic iron signaling and redistribution of iron and cadmium. Involved in ion homeostasis, xylem-to-phloem iron transport and Ion homeostasis and essential for early embryo development.
UOM:
1 * 50 µG
New Product
Fournisseur:
STEMCELL Technologies
Description:
Macrophage colony-stimulating factor (M-CSF) is a homodimeric glycoprotein growth factor that regulates proliferation and differentiation of myeloid hematopoietic progenitor cells to mononuclear phagocytic cell lineages, including monocytes, macrophages, and osteoclasts. M-CSF is a crucial factor for the development of tissue-resident macrophages in most tissues (Ginhoux and Jung). It is required for the maturation and activation of monocytes and macrophages, and regulates inflammatory responses in conjunction with other stimuli such as IFN-γ, LPS, and IL-4 (Murray <i>et al.</i>). M-CSF is also required for bone resorption by osteoclasts, and is involved in the development and regulation of the placenta, mammary gland, and brain. M-CSF is produced by monocytes, fibroblasts, osteoclasts, stromal cells, endothelial cells, and tumor cells (Chockalingam and Ghosh). M-CSF exerts its biological effects by signaling through a receptor tyrosine kinase (CSF-1R or M-CSF-R) encoded by the c-fms proto-oncogene (Hamilton). CSF-1R shares similar structural features with other growth factor receptors, including the stem cell factor (SCF) receptor, platelet-derived growth factor receptor (PDGF-R), and Flt3/Flk-2 receptor tyrosine kinase. Stimulation of the CSF-1R upon binding to M-CSF activates MAPK, PI3K, and PLCγ signaling pathways (Chockalingam and Ghosh). Human and mouse M-CSF sequences are highly conserved both at nucleotide and amino acid levels (80% homology; DeLamarter <i>et al.</i>).
Fournisseur:
Shenandoah Biotechnology
Description:
Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor beta (TGF-β) family and is made by the placenta and cardiovascular tissues. GDF-15 regulates inflammatory and apoptotic pathways during cellular stress and injury. GDF-15 is emerging as a biomarker of early heart disease, such that increased levels of circulating GDF-15 are associated with an increased risk of developing heart failure. The GDF-15 D variant has a Histidine to an Aspartate substitution at amino acid position 7.
Numéro de catalogue:
(PRSI79-956)
Fournisseur:
ProSci Inc.
Description:
Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
UOM:
1 * 1 EA
Numéro de catalogue:
(531-0088)
Fournisseur:
BUCHI
Description:
Gamme d'unités de distillation compactes pour la détermination de l'azote et des protéines à l'aide des méthodes classiques telles que Kjeldahl, TKN (azote total kjeldahl et Devarda). Les unités s'utilisent dans les laboratoires d'analyse de différents secteurs industriels tels que l'agro-alimentaire, l'agriculture, l'environnement, les industries chimiques et pharmaceutiques.
UOM:
1 * 1 ST
Numéro de catalogue:
(PB006C-1-GC)
Fournisseur:
Charles River Laboratories Cell Solutions
Description:
Plasma used for researching the causes, diagnosis, supportive care and treatment of gastric cancer (GC). Patient samples can be used by researchers to investigate biomarker and diagnostic development, pre-clinical research validation, and drug toxicity and efficacy. Human peripheral blood plasma used for researching the causes, diagnosis, supportive care and treatment of gastric cancer (GC). Collected from IRB-consented donors diagnosed with GC.
UOM:
1 * 2 mL
Numéro de catalogue:
(ABCAAB28311-100)
Fournisseur:
Abcam
Description:
Anti-ACE Rabbit Polyclonal Antibody
UOM:
1 * 1 EA
Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(PRSI30-319)
Fournisseur:
ProSci Inc.
Description:
The growth arrest-specific 7 (GAS7) gene is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development.Growth arrest-specific 7 is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development. Several transcript variants encoding proteins which vary in the N-terminus have been described.
UOM:
1 * 1 EA
Numéro de catalogue:
(AATB23070)
Fournisseur:
AAT BIOQUEST INC
Description:
Congo Red has been used as a common qualitative staining method for the identification of amyloids in vitro and in tissue sections.
UOM:
1 * 5 mg
New Product
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