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Masterflex+Single-use+Flow+Sensor
Fournisseur:
Thermo Fisher Scientific
Description:
La pipette Thermo Scientific™ F1-ClipTip™ repose sur une technologie de verrouillage pour assurer une fixation sécurisée des embouts.
Fournisseur:
VITLAB
Description:
En PFA, translucide.
Numéro de catalogue:
(PRSI29-403)
Fournisseur:
ProSci Inc.
Description:
NONO is DNA- and RNA binding protein, involved in several nuclear processes. It binds the conventional octamer sequence in double stranded DNA. It also binds single-stranded DNA and RNA at a site independent of the duplex site. It is involved in pre-mRNA splicing and interacts with U5 snRNA. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs, be involved in DNA unwinding by modulating the function of topoisomerase I/TOP1 and be involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V (D)J recombination and may stabilize paired DNA ends. NONO binds to an enhancer element in long terminal repeats of endogenous intracisternal A particles (IAPs) and activates transcription.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3257)
Fournisseur:
ProSci Inc.
Description:
APOBEC3G Antibody: The Apoliprotein B mRNA-editing, enzyme-catalytic, polypeptide-like (APOBEC) 3 is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3 plays a major role in cellular defense against retroviral infection as at least two isoforms, APOBEC3G and to a lesser extent APOBEC3F, can be incorporated HIV-1 virions and induce hypermutation in the newly synthesized viral DNA and thus destabilize the viral genome. This innate mechanism of retroviral resistance is counteracted by the HIV-1 Vif protein by inducing the ubiquitization and degradation of APOBEC3G; a single amino acid substitution (D128K) blocks APOBEC3G depletion without affecting its inhibitory activity.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4359)
Fournisseur:
ProSci Inc.
Description:
TEM1 Antibody: Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4357)
Fournisseur:
ProSci Inc.
Description:
TEM1 Antibody: Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion.
UOM:
1 * 1 EA
Fournisseur:
Brand
Description:
The Transferpette® S air displacement pipette allows you to work efficiently and ergonomically with both small and large volumes. Due to its perfect ergonomics, the Transferpette® S provides a comfortable grip in any hand position, whether you are right- or left-handed, or have big or small hands.
Numéro de catalogue:
(PRSI25-261)
Fournisseur:
ProSci Inc.
Description:
KCNJ1 has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for KCNJ1.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(28-9269-89)
Fournisseur:
Cytiva
Description:
Phenyl Sepharose 6 Fast Flow is a well-established, standard aromatic HIC medium for capture and intermediate purification requiring low to medium hydrophobicity.Two levels of substitution help find optimal selectivity and binding capacity for a given application.
UOM:
1 * 1 ST
Numéro de catalogue:
(KART1540)
Fournisseur:
KARTELL
Description:
PFA, translucent.
UOM:
1 * 1 ST
Numéro de catalogue:
(VELPF10300305)
Fournisseur:
VELP SCIENTIFIC
Description:
Ces incubateurs DBO ont été conçus pour conserver une température constante pour tous les produits qui nécessitent un contrôle précis de la température. Pour les applications pour lesquelles la surveillance de l'échantillon est extrêmement importante, les modèles I sont parfaits. Le système de thermorégulation de chauffage et de refroidissement contrôlés permet à l'utilisateur de sélectionner une température de fonctionnement située entre +3 et +50 °C. Les modèles E sont équipés d'une connexion sans fil pour TEMPSoft™. Les modèles I sont dotés d'une porte transparente interne et d'une connexion sans fil pour TEMPSoft™ mais aussi d'un système de réglage automatique qui permet le contrôle constant de la température interne, en comparant continuellement les valeurs de consignes et les valeurs détectées et en les alignant via un système d'ajustement précis et rapide. Tous les modèles possèdent 2 prises internes.
UOM:
1 * 1 ST
Fournisseur:
CONSORT
Description:
Électrode, ORP, Électrode de platine ORP (redox), 0...±2000 mV, Jonction unique, scellée, 0...+80 °C, Époxy, Ø×L: 12×110 mm, S7
Numéro de catalogue:
(620-1553)
Fournisseur:
EBRO
Description:
Convient aux mesures lorsque le contact direct est impossible ou difficile. Avec connexion NiCr-Ni
UOM:
1 * 1 ST
Fournisseur:
iST Scientific Ltd
Description:
Transparent, non collant, film sensible à la pression pour plaques qPCR (96 ou 384 puits) et avec fluorescence connue.
Numéro de catalogue:
(PRSI32-230)
Fournisseur:
ProSci Inc.
Description:
Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-949)
Fournisseur:
ProSci Inc.
Description:
Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures.
UOM:
1 * 1 EA
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