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Masterflex+Single-use+Flow+Sensor


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Numéro de catalogue: (BSBTPB9091)

Fournisseur:  BosterBio
Description:   Polyclonal antibody for APP detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. APP information: Molecular Weight: 86943 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit. Cell surface protein that rapidly becomes internalized via clathrin-coated pits. During maturation, the immature APP (N-glycosylated in the endoplasmic reticulum) moves to the Golgi complex where complete maturation occurs (O-glycosylated and sulfated). After alpha-secretase cleavage, soluble APP is released into the extracellular space and the C-terminal is internalized to endosomes and lysosomes. Some APP accumulates in secretory transport vesicles leaving the late Golgi compartment and returns to the cell surface. Gamma-CTF(59) peptide is located to both the cytoplasm and nuclei of neurons. It can be translocated to the nucleus through association with APBB1 (Fe65). Beta-APP42 associates with FRPL1 at the cell surface and the complex is then rapidly internalized. APP sorts to the basolateral surface in epithelial cells. During neuronal differentiation, the Thr-743 phosphorylated form is located mainly in growth cones, moderately in neurites and sparingly in the cell body. Casein kinase phosphorylation can occur either at the cell surface or within a post-Golgi compartment. Associates with GPC1 in perinuclear compartments. Colocalizes with SORL1 in a vesicular pattern in cytoplasm and perinuclear regions; Tissue Specificity: Expressed in all fetal tissues examined with highest levels in brain, kidney, heart and spleen. Weak expression in liver. In adult brain, highest expression found in the frontal lobe of the cortex and in the anterior perisylvian cortex- opercular gyri. Moderate expression in the cerebellar cortex, the posterior perisylvian cortex-opercular gyri and the temporal associated cortex. Weak expression found in the striate, extra- striate and motor cortices. Expressed in cerebrospinal fluid, and plasma. Isoform APP695 is the predominant form in neuronal tissue, isoform APP751 and isoform APP770 are widely expressed in non- neuronal cells. Isoform APP751 is the most abundant form in T- lymphocytes. Appican is expressed in astrocytes.
UOM:  1 * 1 EA
Fournisseur:  Thermo Orion
Description:   This combination pH electrode helps users to precisely conduct pH determinations. Its convenient flat surface tip measures pH in soft, moist surfaces both solid and semi-solid such as agar gel plates, meats, bread dough and similar samples. Compared to conventional electrodes, the proven ROSS reference system exhibits superior stability in measurements, faster response, greater accuracy and precision when measuring samples that vary in temperature or when calibrating in temperatures that differ from the samples.
UOM:  1 * 1 ST
Numéro de catalogue: (HEID591-01910-00)

Fournisseur:  Heidolph Instruments GmbH & Co.KG
Description:   With a high cooling capacity of 600 W and a heating power being almost twice as high, the Hei-CHILL Peltier thermostat is suitable for a large number of temperature control tasks.
UOM:  1 * 1 ST

Fournisseur:  BDP International Inc.
Description:   Le stérilisateur de milieux de culture MediaClave 30, qui permet de fabriquer de 3 à 30 l de milieu nutritif, est un appareil mobile innovant pour la production fiable de milieux de culture aux exigences haut de gamme. Il intègre une technologie de pointe, mais reste simple d'utilisation, ce qui le rend particulièrement adapté aux types de gélose standard et aux milieux à haute sensibilité. Le système de chauffage à flux continu efficace et innovant, l'agitateur magnétique puissant et le processus de refroidissement rapide garantissent la stérilisation sécurisée et homogène des milieux aux températures requises. Le MediaClave 30 est conforme aux dernières exigences pour la documentation de l'appareil et bien sûr aux normes GMP/GLP et FDA CFR 21 Part 11. Avec programme de nettoyage automatique et processus de refroidissement rapide d'une grande efficacité.
UOM: 
Numéro de catalogue: (ILMV2019C-02)

Fournisseur:  Welch by Gardner Denver
Description:   Pumps are constructed with PTFE heads, perfluoroelastomer valves and a PTFE coated molded diaphragm. Includes intake/exhaust hose barbs. DRYFAST® models include tunable vacuum control.
UOM:  1 * 1 ST
Numéro de catalogue: (PRSI3501)

Fournisseur:  ProSci Inc.
Description:   Rheb Antibody: Rheb (Ras homolog enriched in brain) is an evolutionarily conserved member of the Ras family of small GTP-binding proteins originally found to be rapidly induced by synaptic activity in the hippocampus following seizure. While it is expressed at relatively high levels in the brain, Rheb is widely expressed in other tissues and may be induced by growth factor stimulation. Similar to other family members, Rheb triggers activation of the Raf-MEK-MAPK pathway. Biochemical and genetic studies demonstrate that Rheb has an important role in regulating the insulin/Target of rapamycin (TOR) signaling pathway. TOR is a serine/threonine protein kinase that acts as a sensor for ATP and amino acids, balancing the availability of nutrients with protein translation and cell growth. A dimeric protein complex termed TSC1/TSC2 indirectly inhibits TOR activity by inhibiting Rheb via the GAP activity of TSC2.
UOM:  1 * 1 EA
Numéro de catalogue: (PEAK3300253)

Fournisseur:  PEAK SCIENTIFIC
Description:   Genius XE Nitrogen is a cutting-edge evolution combining advanced technology with refined and robust engineering. Genius XE Nitrogen provides a premium standalone nitrogen solution for high performance LC-MS and other critical laboratory applications where performance and reliability are paramount.
UOM:  1 * 1 ST
Numéro de catalogue: (HACH945-252)

Fournisseur:  Hach
Description:   The Radiometer GK2401C combination pH electrode has a glass body, Red-Rod reference system, refillable electrolyte (saturated KCl) and Radiometer Type 7 connector for compatibility with Radiometer MeterLab legacy meters.
UOM:  1 * 1 ST
Numéro de catalogue: (BDAM383512)

Fournisseur:  BD Medical
Description:   The BD Nexiva™ closed IV catheter system is the integrated IV catheter demonstrating longer dwell times and reduced complication rates versus the traditional open system.
UOM:  1 * 80 ST
Numéro de catalogue: (PRSI5447)

Fournisseur:  ProSci Inc.
Description:   NALP3 Antibody: NALP3, a member of Nod-like receptors, has a crucial role in inflammation and immunity and may be a proximal sensor of cellular stress and danger signals. NALP3 forms a caspase-1 activating molecular complex termed the inflammasome. The inflammasome allows activation of IL-1 beta , the key player of the inflammation and fever. NALP3 gene encodes a pyrin like protein which contains a pyrin domain, a nucleotide binding site (NBS) domain, and a leucine rich repeat (LRR) motif. NALP3 protein interacts with apoptosis associated speck like protein containing a CARD and may function as an inducer of apoptosis and an activator of NF-kappa B signaling. Defects in NALP3 have been associated with familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome (MWS), chronic infantile neurological cutaneous and articular (CINCA) syndrome, and neonatal-onset multisystem inflammatory disease (NOMID).
UOM:  1 * 1 EA
Fournisseur:  Welch by Gardner Denver
Description:   The perfect partner for your rotovap. Faster, better quality distillation and solvent concentration.
UOM:  1 * 1 ST
Numéro de catalogue: (662-1556)

Fournisseur:  Thermo Orion
Description:   The ROSS™ series of electrodes provide readings stable to 0,01 pH in less than 30 seconds, even in the extreme case of samples varying from one another by 50 °C or more. Results are three to five times more precise than those obtained with conventional electrodes. And, because drift is less than 0,002 pH per day, restandardisation is minimised.
UOM:  1 * 1 ST
Numéro de catalogue: (IKAA10013210)

Fournisseur:  IKA
Description:   The compact immersion circulators of the lite series are powerful and of high quality, with a focus on essential basic functions, excellent performance and efficient operation.
UOM:  1 * 1 ST
New Product
Fournisseur:  HUBER
Description:   The compact mini chillers are a cost-effective and environmentally friendly cooling solution for numerous laboratory applications.
New Product
Numéro de catalogue: (PRSIPM-4911)

Fournisseur:  ProSci Inc.
Description:   ORAI3 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2. Larger molecular weight bands are sometimes seen in SDS-PAGE; these may represent post-translationally modified ORAI 3.
UOM:  1 * 1 EA
Fournisseur:  PanReac AppliChem
Description:   TRItidy G™ is based on the single step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples (Chomczynski, P. (1993), BioTechniques 15, p.532 - 537). RNA is selectively retained in the aqueous phase during acidic GuSCN/phenol extraction; DNA and proteins are isolated from the organic phase by ethanol and isopropanol precipitation, respectively.
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