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block+heaters+
Numéro de catalogue:
(PRSI76-028)
Fournisseur:
ProSci Inc.
Description:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48 kDa type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI76-225)
Fournisseur:
ProSci Inc.
Description:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-220)
Fournisseur:
ProSci Inc.
Description:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-223)
Fournisseur:
ProSci Inc.
Description:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI76-222)
Fournisseur:
ProSci Inc.
Description:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
UOM:
1 * 0,5 mg
New Product
Numéro de catalogue:
(PRSI76-231)
Fournisseur:
ProSci Inc.
Description:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSIXPS-1021)
Fournisseur:
ProSci Inc.
Description:
p53 has a well established role in the blocking the proliferative action of damaged cells and acting in essence as an anticancer agent. It has been called the guardian of the genome. Phosphorylation of Ser392 in p53 is associated with formation of human tumors. In addition p53 has also been linked to affects of aging and oxidative stress. An increase in p53 has also been linked to deficits in LTP and learning and memory. We raised this polyclonal antibody against a peptide representing the sequence around Ser392 of p53.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI33-135)
Fournisseur:
ProSci Inc.
Description:
The Fibronectin dimer consists of two disulfide linked monomers of approximately 220 kD, and is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing. It accumulates at the site of injury and, along with fibrin, forms a blood clot to stop bleeding and protect damaged tissue. <p>The HFN7.1 Fibronectin antibody is directed against the peptide core and reacts with both the plasma and cellular forms. The antibody blocks the fibronectin-mediated cell attachment not by disrupting the collagen-fibronectin interaction, but by interfering with the attachment of fibronectin to its receptor on the cell surface.
UOM:
1 * 100 µG
New Product
Numéro de catalogue:
(PRSI76-129)
Fournisseur:
ProSci Inc.
Description:
The M1/70 monoclonal antibody specifically reacts with the 170 kDa alpha M integrin chain of mouse CD11b from the Mac-1 integrin (CD11b/CD18). Mac-1 binds to C3bi, CD54 (ICAM-1), and fibrinogen, and it is expressed by granulocytes, macrophages, NK cells, myeloid-derived dendritic cells, microglia, activated lymphocytes, and mouse B-1 cells. The expression is up-regulated on activated neutrophils at the same time that L-selectin is shed from the cell surface. The M1/70 antibody is used for the detection of monocytes, granulocytes, and a subset of natural killer cells in human peripheral blood.M1/70 blocks C3bi binding and cell adherence, but not cell-mediated lysis and it cross-reacts with human CD11b.
UOM:
1 * 0,025 mg
New Product
Numéro de catalogue:
(PRSI79-508)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) hasbeen shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI33-491)
Fournisseur:
ProSci Inc.
Description:
CD22 mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. [UniProt].
UOM:
1 * 1 EA
New Product
Fournisseur:
HAEP LABOR CONSULT
Description:
Thermomixers pour un ou deux blocs, adaptés aux microtubes à essai, aux tubes à centrifuger, aux cuves, aux plaques PCR, aux plaques de microtitrage et aux plaques Deep Well. Une répartition homogène de la température sur l'ensemble du bloc garantit la précision et la reproductibilité sur toute la gamme de températures. Fonction de démarrage automatique, le sens du mouvement peut être modifié via le logiciel, fonction de minuterie : de 1 min à 99,99 h ou fonctionnement continu et documentation via interface USB. Le mouvement brusque des chocs du thermomixer MHL 23 donne lieu à un transfert d'énergie mécanique à l'échantillon, ce qui est particulièrement utile pour les petites quantités.
Numéro de catalogue:
(PRSI33-038)
Fournisseur:
ProSci Inc.
Description:
NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.<p>NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI91-381)
Fournisseur:
ProSci Inc.
Description:
alpha-2-HS Glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.
UOM:
1 * 50 µG
Fournisseur:
Shenandoah Biotechnology
Description:
Beta-Defensin 3 (BD-3), also known as DEFB-3, is a member of the defensin class of antimicrobial peptides. Beta defensins exert host defense responses against viruses, bacteria, and fungi through the binding and permeabilizing of microbial membranes. BD-3 expression is stimulated by interferon-gamma and is an important molecule during adaptive immunity. BD-3 functions to activate monocytes and mast cells, and has antibacterial functions towards Gram-negative and Gram-positive bacteria. Further, BD-3 blocks human immunodeficiency virus type 1 (HIV-1) replication through the downregulation of the HIV-1 co-receptor, CXCR4.
Fournisseur:
BEHR
Description:
CSB 6/E, Bloc chauffant pour 6 tubes à réaction, 20...300 °C, Pour: COD digestion workstations
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