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ENZO LIFE SCIENCES
Numéro de catalogue:
(ENZOBMLSA3610100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 100 µl
New Product
Numéro de catalogue:
(ENZOBMLSA2540100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 100 µl
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
Numéro de catalogue:
(ENZOBMLSA2870100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Recommended Applications: ELISA, Flow Cytometry, ICC, IF, IHC, IHC (FS), IHC (PS), IP, WB
Species reactivity: Human, Mouse, Rat, Sheep, Rabbit, Porcine, Monkey, Ferret, Bovine
UOM:
1 * 100 µl
New Product
Numéro de catalogue:
(ENZOBMLSA4280100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOBMLSA4330020)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 20 µl
New Product
Numéro de catalogue:
(ENZOBMLSA4320100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Mouse, Isotype: IgG1
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
PDK-1 (Pyruvate dehydrogenase kinase-1) is a 48 kDa protein kinase. It is a member of the mitrochondrial matrix protein kinase family and is related to the histidine protein kinases found in prokaryotes. PDK-1 is responsible for phosphorylation and concomitant inactivation of pyruvate dehydrogenase.
Numéro de catalogue:
(ENZOADIKAPTF120E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Acetylation and methylation of lysine are important post-translational modifications that regulate numerous protein-protein and protein-DNA interactions. Lysine acetylation and methylation involves the transfer of acetylCoA, or one or more methyl groups, to the e-amino group of lysine by modifying enzymes and cofactors. Histones and transcription factors are the primary targets of lysine acetylation and methylation, with either modification capable of inducing gene silencing or expression due to differential regulation of cofactors. For example, varying degrees of mono-, di-, and tri-methylation or acetylation of histone H3 at lysine residue 9 are known to demark distinct chromatin regions during various states of gene activation (methylation) or repression (acetylation).
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADIKAMST001E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
β-Catenin, a vertebrate homologue of Drosophila armadillo encoded by the CTNNB1 gene, performs two functions in the cell: mediating cell-cell adhesion by association between E-cadherin and the cytoskeleton, and acting as a downstream transcriptional activator of Wnt signaling, a key player in such functions as embryonic development, the induction of cell polarity, and the determination of cell fate. In the absence of Wnt signaling, glycogen synthase kinase-3β (GSK-3β) phosphorylates any free β-catenin at the amino terminus. This results in adenomatous polyposis coli tumor suppressor protein (APC)-mediated β-catenin degradation via the ubiquitin-proteosome pathway. Wnt signaling stabilizes β-catenin by inhibiting the activity of GSK-3β and preventing β-catenin degradation. β-catenin forms complexes with DNA-binding proteins such as T-cell factor (Tcf) and lymphocyte-enhancer factor (Lef), which promote expression of a variety of target genes, including c-myc and cyclin D1.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADIKAPNO020F)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The diffusible free radical gas nitric oxide (NO) affects a variety of physiological functions, and is a key regulator of the cardiovascular, nervous, and immune systems. NO is synthesized in many tissues from L-arginine, oxygen, and NADPH by three known isoforms of a heme-containing flavoprotein termed NO synthase (nNOS/NOS-I, iNOS/NOS-II, and eNOS/NOS-III). nNOS is a constitutively expressed neuronal NOS isoform that exits in its latent form until it is activated by the binding of calmodulin follo wing elevation of intracellular calcium levels. The C-terminus of nNOS contains a conserved serine residue, Ser1417, analogous to Ser1177 of the constitutively expressed endothelial NOS isoform (eNOS). Phosphorylation of Ser1417 is believed to regulate nNOS activation, particularly in glucose-sensing neurons, where inhibition of AMPK pathways by glucose and leptin serve to suppress nNOS activity, whereas activation of AMPK by insulin leads to nNOS activation.
UOM:
1 * 200 µG
New Product
Numéro de catalogue:
(ENZOBMLPW05750001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
This kit provides the means to quantify 20S proteasome concentrations in biological samples using a sandwich ELISA technique, utilizing two 20S proteasome specific antibodies for capture and detection purposes together with a highly sensitive substrate. Sample 20S proteasome levels are determined by comparison to a 20S proteasome calibration curve produced in parallel. This kit provides sufficient material for 1x96 well plate set-up to be run.
UOM:
1 * 1 KIT
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Sp100 is an interferon-inducible protein and a major constituent of distinct nuclear domains, known as nuclear dots (NDs) or PML bodies. NDs play a role in autoimmunity, virus infections, and in the etiology of acute promyelocytic leukaemia. SUMO modification of Sp100 has been shown to promote interaction of Sp100 with non-histone chromosomal proteins, suggesting a regulatory role in chromatin organization and in functional interplay between these nuclear bodies and chromatin.
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Mouse, Isotype: IgG2a
Numéro de catalogue:
(ENZOBMLPG0170001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Biosynthesis via hydrolysis of prostacyclin. A reliable parameter for measurement of prostacyclin. Ultra-pure.
UOM:
1 * 1 mg
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Prostanoid receptor ligand.
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