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ENZO LIFE SCIENCES
Numéro de catalogue:
(ENZOENZ328936000)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Anti-Biotin Rabbit Polyclonal Antibody
UOM:
1 * 6 mL
New Product
Numéro de catalogue:
(ENZOENZ40849)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The Blur 8 BioProbe® labeled probe is prepared by nick translation of a clone of the human alu repeat sequence. Fragment size range: 100-1000 base pairs (as estimated by agarose gel electrophoresis).
UOM:
1 * 2 µG
New Product
Numéro de catalogue:
(ENZOENZ33802)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Wash Buffer Salts can be used in tissue preparations, immunohistochemical staining procedures and in assays that require HRP-linked detection reagents.
UOM:
1 * 3 L
New Product
Numéro de catalogue:
(ENZOENZ40848)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The BK Virus BioProbe® labeled probe is prepared by nick translation of a clone of the entire BK virus genome. BK virus, a simian polyoma virus, is related to SV40 and also bears some similarity to the human virus JC virus. BK virus is highly tumorigenic in hamsters. Fragment size range: 100-1000 base pairs (as estimated by agarose gel electrophoresis).
UOM:
1 * 2 µG
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>.
Fournisseur:
ENZO LIFE SCIENCES
Description:
The mammalian protein disulphide-isomerase (PDI) family encompasses several highly divergent proteins involved in the processing and maturation of secretory proteins in the ER by catalyzing the rearrangement of disulphide bonds. PDI, an abundant protein of the ER (>400uM), contains a carboxy-terminal retention signal sequence, KDEL, similar to that of BiP and Grp94. The PDI proteins are characterized by the presence of one or more domains of ~95-110 amino acids related to the cytoplasmic protein thioredoxin. All but the PDI-D subfamily are composed entirely of repeats of such domains, with at least one domain containing - and one domain lacking - a redox-active-Cys-X-X-Cys-tetrapeptide. In addition to roles as redox catalysts and isomerases, PDI proteins perform such functions as peptide binding and cell adhesion, and may conduct chaperone activities. Platelet surface thiols and disulphides play an important role in platelet responses. Catalytically active PDI resides on platelet surfaces where it mediates platelet aggregation and secretion by reducing disulfide bonds, thus exposing fibrinogen receptors in platelets.
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>.
Fournisseur:
ENZO LIFE SCIENCES
Description:
Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.
Fournisseur:
ENZO LIFE SCIENCES
Description:
Potent and reversible arginase inhibitor. Specifically interacts with the manganese-cluster of the arginase active site. Does not act as a substrate or as an inhibitor of NOS.
Numéro de catalogue:
(ENZOALX270473M002)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Selective and cell permeable inhibitor of G9a histone methyltransferase.
UOM:
1 * 2 mg
New Product
Numéro de catalogue:
(ENZOALX270464M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
PI3 kinase p110beta inhibitor
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOALX270498M005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
PARP-2 specific inhibitor with 60-fold selectivity for PARP-2 (IC50=0.15 ± 0.04μM) over PARP-1 (IC50=9.0 ± 0.7μM). Can be used for further characterization of PARP-2 in pathophysiological conditions.
UOM:
1 * 5 mg
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Potent inhibitor of histone deacetylases (HDACs) (IC50≤1µM).
Numéro de catalogue:
(ENZOALX270305M005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Selective high affinity inhibitor of P-glycoprotein (MDR1).
UOM:
1 * 5 mg
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Caspase-9 substrate
Numéro de catalogue:
(ENZOALX260088M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Fluorogenic proteasome substrate.
UOM:
1 * 1 mg
New Product
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