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ProSci Inc.
Numéro de catalogue:
(PRSI27-954)
Fournisseur:
ProSci Inc.
Description:
A1BG is a plasma glycoprotein of unknown function. It shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI27-957)
Fournisseur:
ProSci Inc.
Description:
ASGR2 binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5519P)
Fournisseur:
ProSci Inc.
Description:
PPAPDC3 peptide is used for blocking the activity of PPAPDC3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5523P)
Fournisseur:
ProSci Inc.
Description:
TMEM38B peptide is used for blocking the activity of TMEM38B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5529P)
Fournisseur:
ProSci Inc.
Description:
RHBDD3 peptide is used for blocking the activity of RHBDD3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-298)
Fournisseur:
ProSci Inc.
Description:
CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-293)
Fournisseur:
ProSci Inc.
Description:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI46-853)
Fournisseur:
ProSci Inc.
Description:
Anti-GPR142 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5244BT)
Fournisseur:
ProSci Inc.
Description:
NAP2 is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5258BT)
Fournisseur:
ProSci Inc.
Description:
RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI70-951)
Fournisseur:
ProSci Inc.
Description:
Anti-HSP90AA1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI79-265)
Fournisseur:
ProSci Inc.
Description:
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-234)
Fournisseur:
ProSci Inc.
Description:
NF-κ-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-κ-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-241)
Fournisseur:
ProSci Inc.
Description:
Binds and is activated by neuregulins and NTAK.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI2411)
Fournisseur:
ProSci Inc.
Description:
Smac Antibody: The inhibitor of apoptosis proteins (IAPs) regulate programmed cell death by inhibiting members of the caspase family of enzymes. A novel mammalian protein that binds to IAPs and neutralizes the inhibitory effect of IAPs on caspases was recently identified and designated Smac/DIABLO. Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and activates cytochrome c/Apaf-1/capase-9 pathway. Analysis of the structural basis of Smac/DIABLO reveals that the N-terminal amino acids are required for binding of Smac/DIABLO to IAPs and activation of caspases. Smac/DIABLO is expressed in a variety of human and mouse tissues.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI26-743)
Fournisseur:
ProSci Inc.
Description:
3-hydroxyisobutyrate dehydrogenase (3-hydroxy-2-methylpropanoate:NAD (+) oxidoreductase, EC 1.1.1.31) is a dimeric mitochondrial enzyme that catalyzes the NAD (+)-dependent, reversible oxidation of 3-hydroxyisobutyrate, an intermediate of valine catabolism, to methylmalonate semialdehyde.3-hydroxyisobutyrate dehydrogenase (3-hydroxy-2-methylpropanoate:NAD (+) oxidoreductase, EC 1.1.1.31) is a dimeric mitochondrial enzyme that catalyzes the NAD (+)-dependent, reversible oxidation of 3-hydroxyisobutyrate, an intermediate of valine catabolism, to methylmalonate semialdehyde.
UOM:
1 * 50 µG
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