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Addressing challenges when implementing PFAS LC-MS analysis methods for water samples

Webinar

Thursday , 5th December, 2024  
14.00 - 15.00 CET (Berlin, Paris, Madrid)

Replay

Due to their widespread use and persistence in the environment, the determination of PFAS in various matrices, including water, has become one of the most pressing environmental and human health topics of recent years. LC-MS/MS is firmly established as a key analytical technique used to assess their prevalence both in the natural and human environments. However, PFAS analysis by LC-MS is a highly complex and challenging application, due to potentially thousands of target PFAS components, exceptionally low (ppt) detection necessary, varying regulatory requirements and strong potential for the contamination of samples during collection and processing. This webinar draws on experience and challenges encountered in our own lab from setting up targeted LC-MS/MS methods for the analysis of PFAS in water samples. It is aimed to provide guidance to analysts new to, or in the initial stages, of implementing PFAS analysis and will cover topics including: -

  • What are PFAS?
  •  Analytical setup, including delay column use.
  •  Identifying and controlling sources of exogenous sample contamination in the lab.


For more information, please contact us at webinar@avantorsciences.com

Presented By:

Matt_James   

Matt James
 

Matt James is a Senior Research Scientist at Avantor Sciences. Matt gained his PhD at University of Bristol, working on the analysis of archaeological samples and also worked within the pharmaceutical industry. Over the last decade, he has worked within the Technical Support, Applications and R&D teams within Hichrom, part of Avantor. Recent focuses have been HPLC/UHPLC method transfer and translation, the use of solid core phases, development of next generation LC stationary phases and the development of LC methods for key applications, such as the analysis of nitrosamines by LC-MS/MS and PFAS. Matt has co-authored seven peer reviewed articles and presented work at several conferences.