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Eiwitten en peptiden
Itemnummer:
(PRSI90-115)
Leverancier:
ProSci Inc.
Omschrijving:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralisation. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
UOM:
1 * 1 EA
Itemnummer:
(PRSI90-116)
Leverancier:
ProSci Inc.
Omschrijving:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralisation. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
UOM:
1 * 50 µG
Itemnummer:
(PRSI4815P)
Leverancier:
ProSci Inc.
Omschrijving:
HINT1 peptide is used for blocking the activity of HINT1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-149)
Leverancier:
ProSci Inc.
Omschrijving:
CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-168)
Leverancier:
ProSci Inc.
Omschrijving:
Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.
UOM:
1 * 1 EA
Itemnummer:
(PRSI3807P)
Leverancier:
ProSci Inc.
Omschrijving:
AIM peptide is used for blocking activity of AIM antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI2329P)
Leverancier:
ProSci Inc.
Omschrijving:
IKK epsilon peptide is used for blocking the activity of IKK epsilon antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI40-593)
Leverancier:
ProSci Inc.
Omschrijving:
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites. Recombinant murine GM-CSF (40-617) is a 14.2 kDa globular protein consisting of 124 amino acids residues. Recombinant murine GM-CSF (40-621) is a 14.5 kDa globular protein consisting of 128 amino acids residues.
UOM:
1 * 20 µG
Itemnummer:
(PRSI4297P)
Leverancier:
ProSci Inc.
Omschrijving:
PTK7 peptide is used for blocking the activity of PTK7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4293P)
Leverancier:
ProSci Inc.
Omschrijving:
DISC1 peptide is used for blocking the activity of DISC1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4277P)
Leverancier:
ProSci Inc.
Omschrijving:
ADAP peptide is used for blocking the activity of ADAP antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5813P)
Leverancier:
ProSci Inc.
Omschrijving:
FOXO3 peptide is used for blocking the activity of FOXO3 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5563P)
Leverancier:
ProSci Inc.
Omschrijving:
SYNGR1 peptide is used for blocking the activity of SYNGR1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5555P)
Leverancier:
ProSci Inc.
Omschrijving:
PRDM16 peptide is used for blocking the activity of PRDM16 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI40-523)
Leverancier:
ProSci Inc.
Omschrijving:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid residues. Recombinant murine IL-6 is a 21.7 kDa protein containing 187 amino acid residues.
UOM:
1 * 20 µG
Itemnummer:
(PRSI90-319)
Leverancier:
ProSci Inc.
Omschrijving:
Dectin-1 and dectin-2 are type II transmembrane proteins of the C-type lectin family. They contain single carbohydrate recognition domains (CRDs) in their extracellular region. Dectin-1 and dectin-2 are expressed in macrophages and dendritic cells. Dectin-1 recognises beta-glucans with its CRD and signals through its immunoreceptor tyrosine-based activation motif (ITAM)-like motif in the cytoplasmic domain, whereas dectin-2 recognises alpha-mannans and transduces its signal through association with the ITAM-containing Fc receptor gamma-chain.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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