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Numéro de catalogue: (PRSI6807)

Fournisseur:  ProSci Inc.
Description:   TFCP2L1 Antibody: The Transcription factor CP2-like protein 1 (TFCP2L1) is related to the ubiquitously expressed CP2 family of transcription factors that are generally transcription factors. TFCP2L1 is expressed in a developmentally regulated fashion during embryogenesis and in the epithelial lining of distal convoluted tubules in embryonic and adult kidneys. Recent studies have shown that TFCP2L1 is part of an Oct4-centered protein interaction network in embryonic stem cells. It is thought to modulate the activity of other CP2 family members in a cell specific manner, and is itself regulated by sumoylation at a single major site.
UOM:  1 * 1 EA
Fournisseur:  PerkinElmer
Description:   Pure Grade Standards for AA and ICP-OES
UOM:  1 * 1 ST
Fournisseur:  Corning
Description:   Axygen® ImpermaMat sealing mats minimize evaporation in a wide range of temperatures in PCR and storage applications. ImpermaMats are chemically resistant, reusable sealing mats, that provide a high degree of confidence.
Numéro de catalogue: (PRSI91-399)

Fournisseur:  ProSci Inc.
Description:   CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
UOM:  1 * 50 µG
Numéro de catalogue: (AATB484)

Fournisseur:  AAT BIOQUEST INC
Description:   Texas Red® azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through the well known click chemistry.
UOM:  1 * 5 mg
New Product
Numéro de catalogue: (PRSI91-727)

Fournisseur:  ProSci Inc.
Description:   Mucin-15 is a single-pass type I membrane protein member of the Mucin family. Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by epithelial tissues in most metazoans. A key characteristic of Mucins is their ability to form gels. Therefore they are a key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers. Mucin-15 is expressed in many tissues. Mucin-15 is highly glycosylated (N- and O-linked carbohydrates). Mucin-15 may play a role in the cell adhesion to the extracellular matrix.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-819)

Fournisseur:  ProSci Inc.
Description:   TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-540)

Fournisseur:  ProSci Inc.
Description:   Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms ( alpha, beta , gamma , and delta) with identical extracellular domains.
UOM:  1 * 50 µG
Fournisseur:  SHP STERILTECHNIK AG
Description:   Agitateurs magnétiques à position unique colorés à boîtier en PLA. L'entraînement à induction sans usure permet un mélange uniforme pour un maximum de 1 litre de liquide.
Numéro de catalogue: (PRSI29-804)

Fournisseur:  ProSci Inc.
Description:   RGS8 is a member of the regulator of G protein signaling (RGS) family and is a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI26-047)

Fournisseur:  ProSci Inc.
Description:   TFR2,a member of the transferrin receptor-like family,is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III.This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI30-094)

Fournisseur:  ProSci Inc.
Description:   Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
UOM:  1 * 1 EA

Fournisseur:  ProSci Inc.
Description:   Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
UOM:  1 * 50 µG
Fournisseur:  HIRSCHMANN
Description:   The labopette® multi channel pipette for 96 microtiter plates features superior ergonomic characteristics, right down to the smallest detail.
Numéro de catalogue: (PRSI91-890)

Fournisseur:  ProSci Inc.
Description:   CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
UOM:  1 * 50 µG

Fournisseur:  ProSci Inc.
Description:   High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
UOM:  1 * 50 µG
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