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ENZO LIFE SCIENCES
Numéro de catalogue:
(ENZOBMLAK5140001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
FLUOR DE LYS® Green SIRT5 fluorometric drug discovery kit is a sensitive fluorometric assay that measures the lysyl desuccinylase activity of the recombinant human SIRT5.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOBMLAM1000001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Integrin αvβ3 antagonist. Inhibits cell adhesion events mediated by αvβ3. Inhibits angiogenesis. Induces rapid regression of histologically distinct human tumors. Induces apoptosis of angiogenic blood vessels.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOBMLAK5550001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
A Fluor-de-Lys® fluorescent assay system. The SIRT1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT1 included in the kit.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(ENZOBMLAK8220001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The PTP1B Tyrosine Phosphatase Drug Discovery Kit is a colorimetric, non-radioactive assay designed to measure the phosphatase activity of purified PTP1B. This 96-well assay is useful for screening inhibitors and modulators of PTP1B activity.
UOM:
1 * 1 KIT
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
The multifunctional, multi -compartmental protein Calreticulin (Crt) functions as a soluble molecular chaperone of new or misfolded proteins, as well as a Ca2+-binding protein. Most abundant in the ER lumen, Crt expression also occurs in other membrane-bound organelles, the cell surface, and extracellularly. Also known as CRP-55, calregulin and HACBP (high affinity calcium-binding protein), Crt contains the ER-retrieval sequence, KDEL, and is the solub le paralog of the ER membrane protein Calnexin (Cnx). Crt's three domains include a 180 residue N-terminal domain, a proline-rich Pdomainresidues 189 -288) that binds Ca2+ with high affinity and shares homology with Cnx and calmegin, and a 110 residue C-terminal domain that binds Ca2+ with low affinity but high capacity. The P-domain may interact with the co-chaperone ERp57 (Grp58), a thiol reductase. The NMR structure of the P -domain consists of an extended hairpin that appears to form a curved protrusion from the Crt core domain. Both Crt and its membrane bound homolog CNX interact with proteins and glycoproteins possessing monoglucosylated N -glycans. The Crt/Cnx cycle promotes correct folding, inhibits aggregation of folding intermediates, blocks premature oligomerization, regulates ER degradation, and prevents incompletely folded glycoproteins from exiting to the Golgi complex. Crt also appears to function as an auto-antigen in systemic lupus erythematosus, rheumatoid arthritis, celiac disease, complete congenital heart block, and halothane hepatitis. A diversity of additional functions attributed to Crt includes adhesion, blood function, and cardiac and neuronal development gene expression.
Fournisseur:
ENZO LIFE SCIENCES
Description:
Hsp40/Hdj1 is a cytosolic co-chaperone belonging to the class DnaJ, named after its homolog in E. coli. Hsp40 functions in protein folding by binding nascent peptides and unfolded substrates and facilitating substrate interaction with Hsp70. Binding of Hsp40 to Hsp70 increases Hsp70 ATP hydrolysis and substrate binding, which is reversed by the action of nucleotide exchange factors (GrpE in E. coli). Repeated cycles of Hsp40/Hsp70 peptide binding and ATP hydrolysis prevent premature folding and aggregation, promoting protein maturation throughout the cell.
Numéro de catalogue:
(ENZOBMLPR1190010)
Fournisseur:
ENZO LIFE SCIENCES
Description:
A potent inhibitor of the dual specificity phosphatase JSP-1 (IC50=18µM).
UOM:
1 * 10 mg
New Product
Numéro de catalogue:
(ENZOBMLPI1340001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of TNF-alpha processing
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOBMLPI1350001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of TNF-alpha processing
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOADI9002150001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Rapid, easy-to-use ELISA kit to quantify 25(OH) Vitamin D for bone metabolism, nutrition, endocrinology, immunity and cancer.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(ENZOADI901014)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Most sensitive (0,025 pmol/ml) colorimetric kit for intracellular cGMP quantification.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(ENZOADI901153A0001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The most sensitive, specific and flexible alternative to more costly and time-consuming methods for oxytocin detection.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(ENZOADI905638100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Bad is an ~22 kDa pro-apoptotic protein that aids in the initiation of cell death. It exhibits sequence homology to Bcl-2, a protein that prevents apoptosis, within its BH1 and BH2 domains. Bad is phosphorylated at several sites including Ser112, Ser136; phosphorylation by kinases like Akt is known to alter the effects of Bad. Bad has been demonstrated to be phosphorylated at Ser170.
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
MMP inhibitor
Numéro de catalogue:
(ENZOBMLPG0400050)
Fournisseur:
ENZO LIFE SCIENCES
Description:
2,3-Dinor-6-ketoprostaglandin F1α-20,20,20-d3 ≥98% (par CCM), Ultrapure
UOM:
1 * 50 µG
New Product
Numéro de catalogue:
(ENZOBMLPI1210200)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of trypsin and trypsin-like proteases
UOM:
1 * 200 mg
New Product
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