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ProSci Inc.
Numéro de catalogue:
(PRSI42-798)
Fournisseur:
ProSci Inc.
Description:
Anti-FANCL Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-787)
Fournisseur:
ProSci Inc.
Description:
Anti-NDUFS6 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-805)
Fournisseur:
ProSci Inc.
Description:
Anti-NUP107 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5128BT)
Fournisseur:
ProSci Inc.
Description:
Exodus 2 is one of several CC cytokine genes clustered on the p arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterised by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5127BT)
Fournisseur:
ProSci Inc.
Description:
Anti-CCL26 Goat Polyclonal Antibody (Biotin)
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSIXP-5125)
Fournisseur:
ProSci Inc.
Description:
Eotaxin is a 74 amino acid, eosinophil chemotactic CC chemokine originally found in bronchoalveolar lavage fluid from allergic inflammatory subjects. It is involved in regulating the recruitment and activation of inflammatory leukocytes, particularly eosinophils. Eotaxin binds and activates the CCR3 chemokine receptor, and may play a fundamental role in the development of allergic responses.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXP-5122)
Fournisseur:
ProSci Inc.
Description:
EMAP II is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor associated vasculature sensitive to tumor necrosis factor. Its precursor is identical to the p43 subunit, which is associated with the multi tRNA synthetase complex. Therefore, proEMAP II may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.
EMAP II inhibits angiogenesis of vascular beds and suppresses the growth of primary and secondary tumors without affecting normal tissues.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-364)
Fournisseur:
ProSci Inc.
Description:
Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI70-021)
Fournisseur:
ProSci Inc.
Description:
Anti-EBI3 Rat Monoclonal Antibody
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI70-635)
Fournisseur:
ProSci Inc.
Description:
Anti-RPS6 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
Numéro de catalogue:
(PRSI79-697)
Fournisseur:
ProSci Inc.
Description:
A-Raf, B-Raf and c-Raf (Raf-1) are the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway. Activation of c-Raf is the best understood and involves phosphorylation at multiple activating sites including Ser338, Tyr341, Thr491, Ser494, Ser497 and Ser499. p21-activated protein kinase (PAK) has been shown to phosphorylate c-Raf at Ser338 and the Src family phosphorylates Tyr341 to induce c-Raf activity (3, 4). Ser338 of c-Raf corresponds to similar sites in A-Raf (Ser299) and B-Raf (Ser445), although this site is constitutively phosphorylated in B-Raf. Inhibitory 14-3-3 binding sites on c-Raf (Ser259 and Ser621) can be phosphorylated by Akt and AMPK, respectively (6, 7). While A-Raf, B-Raf and c-Raf are similar in sequence and function, differential regulation has been observed (8). Of particular interest, B-Raf contains three consensus Akt phosphorylation sites (Ser364, Ser428 and Thr439) and lacks a site equivalent to Tyr341 of c-Raf (8, 9). The B-Raf mutation V600E results in elevated kinase activity and is commonly found in malignant melanoma (10). Six residues of c-Raf (Ser29, Ser43, Ser289, Ser296, Ser301 and Ser642) become hyperphosphorylated in a manner consistent with c-Raf inactivation. The hyperphosphorylation of these six sites is dependent on downstream MEK signaling and renders c-Raf unresponsive to
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-701)
Fournisseur:
ProSci Inc.
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI79-681)
Fournisseur:
ProSci Inc.
Description:
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSIXW-7017)
Fournisseur:
ProSci Inc.
Description:
beta-1-fetoprotein. beta-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. beta-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of beta-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the beta-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. beta-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of beta-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5659P)
Fournisseur:
ProSci Inc.
Description:
LYRM1 peptide is used for blocking the activity of LYRM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5661P)
Fournisseur:
ProSci Inc.
Description:
LYRM2 peptide is used for blocking the activity of LYRM2 antibody.
UOM:
1 * 50 µG
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