Eiwitten en peptiden
Itemnummer:
(PRSI1151P)
Leverancier:
ProSci Inc.
Omschrijving:
ASK1 peptide is used for blocking the activity of ASK1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-336)
Leverancier:
ProSci Inc.
Omschrijving:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3599P)
Leverancier:
ProSci Inc.
Omschrijving:
TRAF3 peptide is used for blocking the activity of TRAF3 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3627P)
Leverancier:
ProSci Inc.
Omschrijving:
LAMP-2 peptide is used for blocking the activity of LAMP-2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-304)
Leverancier:
ProSci Inc.
Omschrijving:
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. FNDC4 is an ortholog of FNDC5 with 50% identity and 86% similarity compared to Irisin. FNDC4 as well as FNDC5 are extremely well conserved between species. The function of FNDC4 is unknown. The human FNDC4 gene is highly enriched in liver, brain tissue and adipocytes.
UOM:
1 * 1 EA
Itemnummer:
(PRSI5453P)
Leverancier:
ProSci Inc.
Omschrijving:
FRMPD1 peptide is used for blocking the activity of FRMPD1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5435P)
Leverancier:
ProSci Inc.
Omschrijving:
CKIP1 peptide is used for blocking the activity of CKIP1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-711)
Leverancier:
ProSci Inc.
Omschrijving:
High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-700)
Leverancier:
ProSci Inc.
Omschrijving:
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6609P)
Leverancier:
ProSci Inc.
Omschrijving:
ANKLE2 peptide is used for blocking the activity of ANKLE2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5603P)
Leverancier:
ProSci Inc.
Omschrijving:
KLF4 pepide is used for blocking the activity of KLF4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5617P)
Leverancier:
ProSci Inc.
Omschrijving:
MINA peptide is used for blocking the activity of MINA antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI96-270)
Leverancier:
ProSci Inc.
Omschrijving:
EpCAM is also known as CO171A,; EGP; EGP40; GA7332; KSA; M4S; MIC18; MK1; TROP1; hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy.
Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-206)
Leverancier:
ProSci Inc.
Omschrijving:
Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a disulfide-linked homodimeric glycoprotein that belongs to the TGF- beta superfamily. It has been shown to promote the survival of various neuronal subpopulations in both the central as well as the peripheral nervous systems at different stages of their development. Human GDNF cDNA encodes a 211 amino acid residue prepropeptide that is processed to yield a dimeric protein. Mature human GDNF was predicted to contain two 134 amino acid residue subunits. Cells known to express GDNF include Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes and skeletal muscle cells. Mutations in this gene may be associated with Hirschsprung disease.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-398)
Leverancier:
ProSci Inc.
Omschrijving:
CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia. It is reported that CD177 functions as a novel heterophilic binding partner that engages PECAM-1 in membrane-proximal IgD6.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-387)
Leverancier:
ProSci Inc.
Omschrijving:
Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein, which is thought to be a member of the secretin receptor family. It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis. BAI3 is 1498 amino acids in size. It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883), a 7-TM segment, and a C-terminal cytoplasmic region. The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508), and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor. There is one altermate splice form that shows a deletion of aa 643-665. Over aa 25-880, human BAI3 shares 98% aa identity with mouse BAI3. BAI3 has been reported primarily in the brain, but is also localized to lung, testis, and pancreas. It might be involved in angiogenesis inhibition and suppression of glioblastoma.
UOM:
1 * 50 µG
Bel voor prijs
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De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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