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Eiwitten en peptiden
Itemnummer:
(PRSI3401P)
Leverancier:
ProSci Inc.
Omschrijving:
IRF8 peptide is used for blocking the activity of IRF8 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3367P)
Leverancier:
ProSci Inc.
Omschrijving:
SIGIRR peptide is used for blocking the activity of the SIGIRR antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-329)
Leverancier:
ProSci Inc.
Omschrijving:
CCDC134, which is short for Coiled-coil domain-containing protein 134, belongs to the UPF0388 family. It is a 229 aa. protein with a 22 aa. signal peptide, and the last 207 aa. is Coiled-coil domain. This protein is usually expressed in extracellular region.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-400)
Leverancier:
ProSci Inc.
Omschrijving:
Mouse tumour necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumour suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signalling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-433)
Leverancier:
ProSci Inc.
Omschrijving:
Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
UOM:
1 * 1 EA
Itemnummer:
(PRSI92-605)
Leverancier:
ProSci Inc.
Omschrijving:
Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilising peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3269P)
Leverancier:
ProSci Inc.
Omschrijving:
TLR7 peptide is used for blocking the activity of the TLR7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-373)
Leverancier:
ProSci Inc.
Omschrijving:
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
UOM:
1 * 1 EA
Itemnummer:
(PRSI6563P)
Leverancier:
ProSci Inc.
Omschrijving:
PRICKLE2 peptide is used for blocking the activity of PRICKLE2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-078)
Leverancier:
ProSci Inc.
Omschrijving:
Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.
UOM:
1 * 50 µG
Itemnummer:
(PRSI7441P)
Leverancier:
ProSci Inc.
Omschrijving:
13 amino acids near the amino terminus of TFPI.
UOM:
1 * 50 µG
Itemnummer:
(PRSI96-174)
Leverancier:
ProSci Inc.
Omschrijving:
CMRF35-like molecule 9 (CLM-9) is also known as CD300 antigen-like family member G (CD300LG or CD300g), Nepmucin, Triggering receptor expressed on myeloid cells 4 (TREM-4), which belongs to the CD300 family. CD300LG contains one Ig-like V-type (immunoglobulin-like) domain. CD300LG is highly expressed in heart, skeletal muscle and placenta. CD300LG is a receptor which may mediate L-selectin-dependent lymphocyte rollings. CD300LG binds SELL in a calcium dependent manner and also binds lymphocyte.
UOM:
1 * 1 EA
Itemnummer:
(PRSI92-354)
Leverancier:
ProSci Inc.
Omschrijving:
Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilises intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-350)
Leverancier:
ProSci Inc.
Omschrijving:
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyses both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI2021P)
Leverancier:
ProSci Inc.
Omschrijving:
DcR2 peptide is used for blocking the activity of DcR2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI2055P)
Leverancier:
ProSci Inc.
Omschrijving:
FLIP peptide is used for blocking the activity of FLIP antibody.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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