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Eiwitten en peptiden
Itemnummer:
(PRSI91-097)
Leverancier:
ProSci Inc.
Omschrijving:
Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family, which involved in immunoregulatory and inflammatory processes. CCL26 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. Eotaxin-3/CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for Eotaxin-3 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant Eotaxin-3 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, Eotaxin-3 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6097P)
Leverancier:
ProSci Inc.
Omschrijving:
ZIP9 peptide is used for blocking the activity of ZIP9 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6093P)
Leverancier:
ProSci Inc.
Omschrijving:
ZIP7 peptide is used for blocking the activity of ZIP7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6109P)
Leverancier:
ProSci Inc.
Omschrijving:
REQUIEM peptide is used for blocking the activity of REQUIEM antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4619P)
Leverancier:
ProSci Inc.
Omschrijving:
Wnt10b peptide is used for blocking the activity of Wnt10b antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4621P)
Leverancier:
ProSci Inc.
Omschrijving:
LIMP2 peptide is used for blocking the activity of CSN8 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4303P)
Leverancier:
ProSci Inc.
Omschrijving:
STEAP1 peptide is used for blocking the activity of STEAP1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-308)
Leverancier:
ProSci Inc.
Omschrijving:
Coxsackievirus and Adenovirus Receptor (CAR) belongs to the CTX family of the Ig superfamily. CXADR is a type I transmembrane glycoprotein and expressed in pancreas, brain, heart, small intestine, testis, prostate. It is a receptor that mediates gene transfer and also act as an adhesion molecule within junctional complexes, notably between epithelial cells lining body cavities and within myocardial intercalated discs. CXADR contains an extracellular domain, a transmembrane helix and a C-terminal intracellular domain. The C-terminal interacts with few cytoplasmic junctional proteins, microtubules and the actin cytoskeleton.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-313)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin 7 Receptor alpha (IL-7R alpha), also known as CD127, is a 75 kDa hematopoietin receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7R alpha is majorly expressed on T cells and their precursors, and early in B cell development as well, prior to the appearance of surface IgM. Dynamic regulation of IL-7R alpha is important for the generation of appropriate immune responses.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-321)
Leverancier:
ProSci Inc.
Omschrijving:
Cathepsin A is active in cellular compartments called lysosomes. These compartments contain enzymes that digest and recycle materials when they are no longer needed. Cathepsin A interacts with the enzymes beta -galactosidase and neuraminidase 1, which play a role in the breakdown of complexes of sugar molecules (oligosaccharides) attached to certain proteins (glycoproteins) or fats (glycolipids). Cathepsin A forms a complex with these two enzymes and directs their transport within the cell to the lysosomes. Within lysosomes, cathepsin A activates the enzymes and prevents their breakdown.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-323)
Leverancier:
ProSci Inc.
Omschrijving:
SPOCK3，also called Testican3,is a secreted protein and make up a family of extracellular heparan/chondroitin sulphate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain and mainly expressed in brain. SPOCK3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-749)
Leverancier:
ProSci Inc.
Omschrijving:
Insulin-Like Growth Factor-Binding Protein 5 (IGFBP-5) is a secreted protein that belongs to the insulin-like growth factor (IGF) binding proteins superfamily. Members of this family prolong the half-life of the IGFs. They have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. IGFBP-5 contains one IGFBP N-terminal domain and one thyroglobulin type-1 domain. IGFBP-5 is expressed by fibroblasts, myoblasts and Osteosarcoma. It is also present at lower levels in liver, kidney, and brain.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-752)
Leverancier:
ProSci Inc.
Omschrijving:
Reticulocalbin-3 is a member of the CREC family that is involved in the secretory pathway. Members of the CREC family consist of a number of multiple EF-hand domains. Reticulocalbin-3 localizes to the endoplasmic reticulum lumen. The bioinformaticanalysis of Reticulocalbin-3 reveal that it is a putative Ca2+-binding protein. In addition, it has been shown that autoactivation and secretion of PACE4 was increased upon co-expression with Reticulocalbin-3. The proPACE4-RCN-3 complex is plays an important role in the biosynthesis of PACE4.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-201)
Leverancier:
ProSci Inc.
Omschrijving:
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. FABP6 plays a role in fatty acid uptake, transport, and metabolism. FABP6 stimulates gastric acid and pepsinogen secretion. It seems to be able to bind to bile salts and bilirubins.
UOM:
1 * 50 µG
Itemnummer:
(PRSI40-588)
Leverancier:
ProSci Inc.
Omschrijving:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant murine FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4649P)
Leverancier:
ProSci Inc.
Omschrijving:
Slc35D1 peptide is used for blocking the activity of Slc35D1 antibody.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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