Print…- Startpagina > Eiwitten en peptiden
U heeft gezocht op:
11 231 Er zijn resultaten gevonden.
Eiwitten en peptiden
Itemnummer:
(PRSI91-215)
Leverancier:
ProSci Inc.
Omschrijving:
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-220)
Leverancier:
ProSci Inc.
Omschrijving:
NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in the dense fibrillar component of the nucleolus. NHP2L1 has been shown to interact with RAD17and PRPF31. The protein undergoes a conformational change upon RNA-binding. NHP2L1 binds to the 5-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly, prior to step I of splicing catalysis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-219)
Leverancier:
ProSci Inc.
Omschrijving:
Neurocalcin-delta (NCALD) is a neuronal calcium-binding protein that belongs to the neuronal calcium sensor (NCS) family. It expressed in mammalian brains. NCALD contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein possesses a Ca2+ /myristoyl switch. It is cytosolic at resting calcium levels. However, elevated intracellular calcium levels induce a conformational change which exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. NCALD protein is thought to be a regulator of G protein-coupled receptor signal transduction.
UOM:
1 * 50 µG
Itemnummer:
(PRSI7281P)
Leverancier:
ProSci Inc.
Omschrijving:
17 amino acids near the carboxy terminus of human MTERFD1.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-926)
Leverancier:
ProSci Inc.
Omschrijving:
Glial Cell Line-Derived Neurotrophic Factor Family Receptor alpha-1 (GDNFR alpha1) is a glycosylphosphatidylinositol (GPI) linked cell surface protein belonging to GDNF-family receptor alpha subtype which consists of at least four members. GFR alpha1and GFR alpha2 are the cognate co-receptor for the neurotrophic factor neurturin mediating the NRTN-induced autophosphorylation and activation of the RET tyrosine kinase receptor. Soluble GFR alphas released enzymatically from the cell surface by phosphatidylinositol phospholipase C, as well as recombinantly produced soluble GFR alpha1, can also bind with high affinity to GDNF and trigger the activation of Ret tyrosine kinase. Human GFR alpha1 shares 93% amino acid identity with mouse GFR alpha1.The expression of the various GFR alphas are differentially regulated in the central and peripheral nervous system, suggesting complementary roles for the GFR alphas in mediating the activities of the GDNF family of neurotrophic factors.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5437P)
Leverancier:
ProSci Inc.
Omschrijving:
GAS peptide is used for blocking the activity of GAS antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-038)
Leverancier:
ProSci Inc.
Omschrijving:
Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulphide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumour growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodelling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-036)
Leverancier:
ProSci Inc.
Omschrijving:
Retinol binding protein 4 (RBP4; RBP) is a 21kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
UOM:
1 * 1 EA
Itemnummer:
(PRSI3595P)
Leverancier:
ProSci Inc.
Omschrijving:
IRAK2 peptide is used for blocking the activity of IRAK2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3583P)
Leverancier:
ProSci Inc.
Omschrijving:
T-cadherin peptide is used for blocking the activity of T-cadherin antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3579P)
Leverancier:
ProSci Inc.
Omschrijving:
CTRP7 peptide is used for blocking the activity of the CTRP7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-238)
Leverancier:
ProSci Inc.
Omschrijving:
GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-345)
Leverancier:
ProSci Inc.
Omschrijving:
GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodelling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.
UOM:
1 * 2 µG
Itemnummer:
(PRSI90-338)
Leverancier:
ProSci Inc.
Omschrijving:
TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell surface by metalloproteases to form a soluble molecule. Active TRAIL forms trimers and specifically binds to five distinct receptors: TRAIL-R1 (DR4; Apo2;CD261; TNFRSF10A), TRAIL-R2 (DR5; KILLER; TRICK2A;TRICK2B; CD262; TNFRSF10B), TRAIL-R3 (DcR1;LIT; TRID; CD263; TNFRSF10C), TRAIL-R4 (DcR2; TRUNDD; CD264; TNFRSF10D), and osteoprotegerin (OPG; OCIF; TNFRSF11B). Trimerised TRAIL triggers apoptosis upon ligation of cell surface TRAIL-R1 and/or TRAIL-R2 by inducing the formation of the so-called multiprotein death-inducing signalling complex (DISC).
UOM:
1 * 20 µG
Itemnummer:
(PRSI90-505)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-15 (IL-15) has a broad spectrum of biological activities. It is crucial for the development, proliferation, survival and differentiation of multiple cells from both innate and adaptive immune systems. IL-15 up-regulation has a central role in the development of several autoimmune or chronic inflammatory disorders. Targeting IL-15 or its receptor may have a valuable impact on the treatment of immune-mediated diseases. IL-15 participates in the development of important immune antitumour mechanisms. It activates CD8(+) T cells, natural killer (NK) cells, NK T cells, and can promote the formation of antitumour antibodies. IL-15 can also protect T effector cells from the action of T regulatory cells and reverse tolerance to tumour-associated antigens. In pre-clinical studies IL-15 has been found to demonstrate potentiated antitumour effects following pre-association with IL-15Ralpha, or when used in combination with chemotherapy, adoptive therapy, monoclonal antibodies, and tumour vaccines.
Application: Useful for immunofluorescent staining and flow cytometric analysis to identify and enumerate IL-15Ralpha expressing cells within mixed cell populations.
UOM:
1 * 1 VIA
Itemnummer:
(PRSI2509P)
Leverancier:
ProSci Inc.
Omschrijving:
Caspase-14 peptide is used for blocking activity of caspase-14 antibody.
UOM:
1 * 50 µG
Bel voor prijs
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
Bijkomende documentatie kan noodzakelijk zijn voor dit item. Een VWR-verantwoordelijke zal contact opnemen met u indien nodig.
Producten die gemarkeerd zijn met dit symbool werden geblokkeerd door uw organisatie. Gelieve contact op te nemen met uw aankoopafdeling
Het originele artikel is niet langer beschikbaar. Het getoonde alternatief is wel beschikbaar.
Product(en) met dit symbool worden binnenkort niet meer verkocht - verkoop tot het einde voorraad. Alternatieven zijn mogelijk beschikbaar door te zoeken met het VWR artikelnummer dat hierboven wordt vermeld. Neem voor meer informatie contact op met onze Customer Service op 016 385 011.
|
|||||||||
Lijst
