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Eiwitten en peptiden
Itemnummer:
(PRSI92-030)
Leverancier:
ProSci Inc.
Omschrijving:
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-035)
Leverancier:
ProSci Inc.
Omschrijving:
Cyclin-Dependent Kinase Inhibitor 1 (CDKN1A) is a member of the CDI family. CDKN1A is widely expressed in all adult tissues, but low expressed in the brain tissue. CDKN1A can be induced by p53/TP53, mezerein and IFNB1, repressed by HDAC1. CDKN1A may be an important intermediate, by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage, CDKN1A can bind to and inhibit cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-033)
Leverancier:
ProSci Inc.
Omschrijving:
Zinc Finger Protein 70 (ZNF70) is a member of the krueppel C2H2-type zinc-finger protein family. ZFN70 is localized to the cell nucleus and contains eleven C2H2-type zinc fingers. ZFN70 has sequence-specific DNA binding transcription factor activity, and it may be involved in transcriptional regulation. In addition, ZFN70 has the DNA-binding and metal-binding activity, which can bind zinc ion.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-619)
Leverancier:
ProSci Inc.
Omschrijving:
PTP4A2, also known as PRL2 or PTPCAAX2, is short for Protein tyrosine phosphatase type IVA 2. This protein exists in cell membrane, cytoplasm,endosome and membrane. PTP4A2 is often farnesylated during post-translational modification. Farnesylation is required for membrane targeting and for interaction with RABGGTB. The unfarnesylated forms are redirected to the nucleus and cytosol. It can stimulate progression from G1 into S phase during mitosis and promotes tumors. It also inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-616)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-613)
Leverancier:
ProSci Inc.
Omschrijving:
SLAM family member 8(SLAMF8) is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF8 encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. The protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-607)
Leverancier:
ProSci Inc.
Omschrijving:
Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4777P)
Leverancier:
ProSci Inc.
Omschrijving:
gp120 peptide is used for blocking the activity of presenilin1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4789P)
Leverancier:
ProSci Inc.
Omschrijving:
Aldh3A2 peptide is used for blocking the activity of Aldh3A2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4765P)
Leverancier:
ProSci Inc.
Omschrijving:
POFUT1 peptide is used for blocking the activity of POFUT1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI40-608)
Leverancier:
ProSci Inc.
Omschrijving:
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant rat SCF is an 18.4 kDa polypeptide containing 154 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
UOM:
1 * 1 EA
Itemnummer:
(PRSI6217P)
Leverancier:
ProSci Inc.
Omschrijving:
GLS2 peptide is used for blocking the activity of GLS2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6221P)
Leverancier:
ProSci Inc.
Omschrijving:
LRRFIP2 peptide is used for blocking the activity of LRRFIP2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6219P)
Leverancier:
ProSci Inc.
Omschrijving:
LRRFIP1 peptide is used for blocking the activity of LRRFIP1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6211P)
Leverancier:
ProSci Inc.
Omschrijving:
BAPX1 peptide is used for blocking the activity of BAPX1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5851P)
Leverancier:
ProSci Inc.
Omschrijving:
SCRN2 peptide is used for blocking the activity of SCRN2 antibody.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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