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acids+and+salts+high+purity
Numéro de catalogue:
(PRSI31-051)
Fournisseur:
ProSci Inc.
Description:
MDM4 inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. inhibits degradation of MDM2. It can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation and apoptotic functions.The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 1 EA
Fournisseur:
MP Biomedicals
Description:
Cetyltrimethylammonium bromide is a phase transfer catalyst ideal for the precipitation of DNA. Hexadecyltrimethylammonium bromide is a bactericidal, cationic detergent. Its activity is neutralized by soaps and anionic detergents (i.e., SDS). Trimethylammonium bromide compounds form insoluble complexes with SDS. It is active at alkaline pH against both Gram positive and Gram negative organisms.
Cetyltrimethylammonium bromide ia used as an cationic surfactant suitable for the isolation of high molecular weight DNA in plants and other organisms(by a rapid method) as well as plant DNA for use in PCR analysis. It has been used to precipitate nucleic acids. CTAB provides enhancement of Concanavalin A mediated agglutination. It has been used for the determination of protein molecular weights in electrophoretic systems and for determination of critical micelle concentration of detergents. CTAB has also been used as a titrant for potentiometric titration of perchlorate and as a phase-transfer catalyst in reduction of arenes and heterocyclic compounds.
Numéro de catalogue:
(1.17081.1000)
Fournisseur:
Merck
Description:
The hematoxylin and eosin (H&E) staining method is the method most frequently used for the staining of histology material of human origin.
UOM:
1 * 1 L
Numéro de catalogue:
(86C-1KT)
Fournisseur:
SIGMA-ALDRICH MICROSCOPY
Description:
Leukocyte Alkaline Phosphatase (LAP) kits are intended for the semi-quantitative demonstration of alkaline phosphatase activity in white blood cells.
UOM:
1 * 1 KIT
Numéro de catalogue:
(786-401)
Fournisseur:
G-Biosciences
Description:
OmniPrep™ for Mouse Tail Kit isolates high quality genomic DNA from mouse tail samples. If used according to the protocols this kit purifies DNA from 100 to 200 cm mouse tail.
UOM:
1 * 1 KIT
Fournisseur:
G-Biosciences
Description:
NDSB 201 is a zwitterionic compound. Unlike zwitterionic detergents, the hydrophobic group in NDSB 201 is too short to form micelles, even at 1 M concentrations. NDSB 201 can be used for the purification of proteins and solubilisation of protein samples for 2D gel electrophoresis.
Numéro de catalogue:
(BC12)
Fournisseur:
G-Biosciences
Description:
m-Maleimidobenzoyl-N-hydroxysulfosuccinimide esterHeterobifunctional Cross Linker
UOM:
1 * 100 mg
Fournisseur:
VWR Chemicals
Description:
DPBS is commonly used salt solution in cell enumeration as a diluent, for rinsing cells and as a buffer in many chromatographic procedures. DPBS is also used in FACS (Fluorescence-Activated Cell Sorting) process to wash and re-suspend cells during the dissociation process, as well as for many analytical methods or biochemical treatments.
Numéro de catalogue:
(40020-1)
Fournisseur:
Biotium
Description:
5-Aminoallyl-dUTP (AA-dUTP) can be enzymatically incorporated into DNA. The resulting amine-containing DNA can be subsequently labeled with a fluorescent dye, biotin or other haptens via conventional peptide coupling method.
UOM:
1 * 1 mg
Numéro de catalogue:
(TCIAT1423-25G)
Fournisseur:
TCI
Description:
L-Tyrosine sel disodique hydraté ≥98.0% (par HPLC, analyse par titration)
UOM:
1 * 25 g
Numéro de catalogue:
(1.09945.0001)
Fournisseur:
Merck
Description:
Sodium chlorure 0.1 mol/l en solution aqueuse concentrée, Titrisol®, Supelco®
UOM:
1 * 1 Ampul
Numéro de catalogue:
(PRSI79-324)
Fournisseur:
ProSci Inc.
Description:
Chek1 is a protein kinase that inhibits mitotic entry after DNA damage, required for the DNA damage checkpoint and is strongly similar to murine Chek1. Checkpoint pathways control the order and timing of cell cycle transitions and ensure that critical events, such as DNA replication and chromosome segregation, are completed with high fidelity. The mouse and human proteins share 90% sequence identity through the protein kinase domains. The sequence of the 476-amino acid human Chek1 protein is 29%, 40%, and 44% identical to those of the fission yeast Chek1, C. elegans Chek1, and Drosophila 'grapes' (Grp) proteins, respectively. Chek1 is expressed ubiquitously as an approximately 2.4-kb mRNA, with the most abundant expression in thymus, testis, small intestine, and colon. The protein has altered mobility when isolated from cells treated with ionizing radiation, indicating that Chek1 is modified in response to DNA damage. In vitro, Chek1 directly phosphorylates a regulator of CDC2 tyrosine phosphorylation, CDC25C. In response to DNA damage, Chek1 phosphorylates and inhibits CDC25C, thus preventing activation of the CDC2-Cyclin-B complex and mitotic entry
UOM:
1 * 1 EA
Numéro de catalogue:
(22525.296)
Fournisseur:
VWR Chemicals
Description:
Carboxyméthylcellulose, sel de sodium, TECHNICAL, viscosité moyenne
UOM:
1 * 1 kg
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.
Numéro de catalogue:
(TCIAD5318-250MG)
Fournisseur:
TCI
Description:
1,2-Dioleoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt ≥98.0% (par analyse titrimétrique)
UOM:
1 * 250 mg
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