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Numéro de catalogue: (PRSI26-891)

Fournisseur:  ProSci Inc.
Description:   AMN1 belongs to the AMN1 family. The exact function of AMN1 remains unknown.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI26-889)

Fournisseur:  ProSci Inc.
Description:   The exact function of C12orf42 remains unknown.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI26-885)

Fournisseur:  ProSci Inc.
Description:   HAGH is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI3979P)

Fournisseur:  ProSci Inc.
Description:   PEN2 peptide is used for blocking activity of PEN2 antibody.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI3963P)

Fournisseur:  ProSci Inc.
Description:   sRANK-L peptide is used for blocking activity of sRANK-L antibody.
UOM:  1 * 50 µG

Fournisseur:  ProSci Inc.
Description:   Anti-Borrelia burgdorferi Mouse Monoclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI28-473)

Fournisseur:  ProSci Inc.
Description:   ZNF713 is a new candidate transcription factor.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI28-459)

Fournisseur:  ProSci Inc.
Description:   ZNF488 is a candidate transcription factor
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI4963)

Fournisseur:  ProSci Inc.
Description:   Gle1 Antibody: The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI4945)

Fournisseur:  ProSci Inc.
Description:   PIG-Y Antibody: Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA.
UOM:  1 * 1 EA

Fournisseur:  ProSci Inc.
Description:   West Nile Virus Matrix Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSIXP-5194BT)

Fournisseur:  ProSci Inc.
Description:   IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL-6 appears to interact with IL2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSIXP-5200)

Fournisseur:  ProSci Inc.
Description:   IL-9 is a cytokine preferentially produced by T helper type 2 lymphocytes and active on various cell types such as T and B lymphocytes, mast cells and haemopoietic progenitors; but no effect of this cytokine has been reported so far on mononuclear phagocytes. IL-9 stimulates cell proliferation and prevents apoptosis. The IL-9 receptor (IL 9R) belongs to the haemopoietic receptor superfamily and its signal transduction involves mainly the (JAK/STAT) pathway. Some studies have implicated IL-9 as an important cytokine in a number of Th2 cytokine mediated pathologies, in particular asthma
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI91-498)

Fournisseur:  ProSci Inc.
Description:   V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco)protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains, in several T-cell receptors such as CD2 (Cluster of Differentiation 2), CD4, CD80, and CD86, in myelin membrane adhesion molecules, in junction adhesion molecules (JAM), in tyrosine-protein kinase receptors, and in the programmed cell death protein 1 (PD1). It shows expression in stomach and prostate by Northern blot, and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-490)

Fournisseur:  ProSci Inc.
Description:   CD98 is a single-pass type I I membrane protein which belongs to the SLC3A transporter family. SLC3A2/MDU1 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. It consists of an 85 kDa glycosylated type II transmembrane heavy chain and a 40-50 kDa non-glycosylated light chain with 12 transmembrane segments. The heavy chain (SLC3A2) pairs with one of several light chains (SLC7A5, 6, 7, 8, 10, or 11) and is required for the cell surface expression and amino acid transport function of the light chains. It is involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. It also mediates integrin signaling, T cell costimulation, B cell proliferation, and viral fusion with cell membranes.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI28-919)

Fournisseur:  ProSci Inc.
Description:   TRIM28 mediates transcriptional control by interaction with the Kruppel-associated box repression domain found in many transcription factors. TRIM28 localizes to the nucleus and is thought to associate with specific chromatin regions. It is a member of the tripartite motif family. This tripartite motif includes three zinc-binding domains, a RING,a B-box type 1 and a B-box type 2, and a coiled-coil region.
UOM:  1 * 1 EA
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