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Protéines et Peptides
Numéro de catalogue:
(PRSI5529P)
Fournisseur:
ProSci Inc.
Description:
RHBDD3 peptide is used for blocking the activity of RHBDD3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-298)
Fournisseur:
ProSci Inc.
Description:
CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-293)
Fournisseur:
ProSci Inc.
Description:
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. By binding to PD1 on activated T-cells and B-cells, PD-L1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. Accordingly, it leads to growth of immunogenic tumor growth by increasing apoptosis of antigen specific T cells and may contribute to immune evasion by cancers. PD-L1 thus is regarded as promising therapeutic target for human autoimmune disease and malignant cancers.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-279)
Fournisseur:
ProSci Inc.
Description:
Flagellin is the subunit protein which polymerises to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3503P)
Fournisseur:
ProSci Inc.
Description:
TSC1 peptide is used for blocking the activity of the TSC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3515P)
Fournisseur:
ProSci Inc.
Description:
PTEN peptide is used for blocking the activity of the PTEN antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7013P)
Fournisseur:
ProSci Inc.
Description:
TET3 peptide is used for blocking the activity of TET3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6987P)
Fournisseur:
ProSci Inc.
Description:
TOX peptide is used for blocking the activity of TOX antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7017P)
Fournisseur:
ProSci Inc.
Description:
DLK1 peptide is used for blocking the activity of DLK1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3513P)
Fournisseur:
ProSci Inc.
Description:
4E-BP1 peptide is used for blocking the activity of 4E-BP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3507P)
Fournisseur:
ProSci Inc.
Description:
TSC2 peptide is used for blocking the activity of the TSC2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6789P)
Fournisseur:
ProSci Inc.
Description:
NCLN peptide is used for blocking the activity of NCLN antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3135P)
Fournisseur:
ProSci Inc.
Description:
TLR2 peptide is used for blocking the activity of TLR2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2003P)
Fournisseur:
ProSci Inc.
Description:
ICAD peptide is used for blocking the activity of ICAD antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4473P)
Fournisseur:
ProSci Inc.
Description:
Slitrk4 peptide is used for blocking the activity of Slitrk4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-410)
Fournisseur:
ProSci Inc.
Description:
Insulin-like growth factor 1 (IGF-1) is also known as somatomedin C, IGF1A, IGFI, sulfation factor, and is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons. IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. IGF-1 binds to at least two cell surface receptors: the Insulin-like growth factor 1 receptor, abbreviated as "IGF1R", and the insulin receptor. The IGF-1 receptor seems to be the "physiologic" receptor - it binds IGF-1 at significantly higher affinity than the IGF-1 that is bound to the insulin receptor. Like the insulin receptor, the IGF-1 receptor is a receptor tyrosine kinase - meaning it signals by causing the addition of a phosphate molecule on particular tyrosines. Its primary action is mediated by binding to its specific receptor IGF1R, present on many cell types in many tissues. Binding to the IGF1R, a receptor tyrosine kinase, initiates intracellular signaling; IGF-1 is one of the most potent natural activators of the AKT signaling pathway, a stimulator of cell growth and proliferation, and a potent inhibitor of programmed cell death. Insulin-like growth factor 1 has been shown to bind and interact with all the IGF-1 Binding Proteins (IGFBPs), of which there are six (IGFBP1-6). Specific references are provided for interactions with IGFBP3, IGFBP4 and IGFBP7.
UOM:
1 * 1 EA
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