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Protéines et Peptides
Numéro de catalogue:
(PRSI91-070)
Fournisseur:
ProSci Inc.
Description:
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-078)
Fournisseur:
ProSci Inc.
Description:
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the receptor for CCL27/CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5119P)
Fournisseur:
ProSci Inc.
Description:
Norrin peptide is used for blocking the activity of Norrin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5121P)
Fournisseur:
ProSci Inc.
Description:
ZBED2 peptide is used for blocking the activity of ZBED2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5123P)
Fournisseur:
ProSci Inc.
Description:
ZBED3 peptide is used for blocking the activity of ZBED3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-127)
Fournisseur:
ProSci Inc.
Description:
Glutamate Oxaloacetate Transaminase 1 (GOT1) is a cytoplasmic protein. GOT1 belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. GOT1 is a pyridoxal phosphate-dependent enzyme that exists in cytoplasmic and mitochondrial forms. GOT1 plays a key role in amino acid metabolism and the urea and tricarboxylic acid cycles. GOT1 involves in L-methionine salvage from methylthioadenosine, aspartate catabolic process, cellular response to insulin stimulus, polyamine metabolic process, and glucocorticoid stimulus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-171)
Fournisseur:
ProSci Inc.
Description:
DLK2 regulates adipogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6517P)
Fournisseur:
ProSci Inc.
Description:
DRGX peptide is used for blocking the activity of DRGX antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6497P)
Fournisseur:
ProSci Inc.
Description:
Strumpellin peptide is used for blocking the activity of Strumpellin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-634)
Fournisseur:
ProSci Inc.
Description:
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo receptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-327)
Fournisseur:
ProSci Inc.
Description:
T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4489P)
Fournisseur:
ProSci Inc.
Description:
LGI1 peptide is used for blocking the activity of LGI1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4491P)
Fournisseur:
ProSci Inc.
Description:
LGI2 peptide is used for blocking the activity of LGI2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-862)
Fournisseur:
ProSci Inc.
Description:
Limbic system-associated membrane protein is also known as LSAMP, IgLON family member 3. In humans, it is encoded by the LSAMP gene. It belongs to the immunoglobulin superfamily and contains 3 Ig-like C2-type domains. Limbic system-associated membrane protein mediates selective neuronal growth and axon targeting. It contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. It is also essential for normal growth of the hyppocampal mossy fiber projection
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-861)
Fournisseur:
ProSci Inc.
Description:
Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-309)
Fournisseur:
ProSci Inc.
Description:
Cystatin-M is a typical secretory protein. It is synthesized as a preprotein with a patent N-terminal signal sequence.It belongs to the cystatin family. The most widely accepted function of cystatins is that of protease inhibitors. Most cysteine proteases are confined within cells where optimal pH and redox conditions favor their enzymatic activity. Thus, the majority of intracellular cysteine proteases are inactivated by oxidizing conditions outside the cells. Among the various types of intracellular cysteine proteases, cystatins seem to target preferentially endosomal/lysosomal cysteine proteases of the papain family, such as cathepsin B, cathepsin K/O2, cathepsin L, cathepsin L2/V and cathepsin S. Another important function of Cst6 seems to be in the terminal differentiation of stratified squamous epithelial cells and in the formation of cornified envelops. Cst6 is believed to be important in fine-tuning the enzymatic activities of endosomal/lysosomal cysteine proteases such as cathepsin L, cathepsin L2/V and AEP/mammalian legumain. Deregulated activity of these proteases could lead to abnormal activation of transglutaminases and disorders in cornification.
UOM:
1 * 50 µG
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