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Protéines et Peptides
Numéro de catalogue:
(PRSI5143P)
Fournisseur:
ProSci Inc.
Description:
APP peptide is used for blocking the activity of APP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5153P)
Fournisseur:
ProSci Inc.
Description:
erbB-2 peptide is used for blocking the activity of RUNX1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-339)
Fournisseur:
ProSci Inc.
Description:
Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells, monocytes, and dendritic cells, highly in naive T-cells and B-cells. As an inhibitory receptor, LAIR1 plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. LAIR1 plays inhibitory role independently of SH2-containing phosphatases and modulates cytokine production in CD4+ T-cells. It down-regulates IL2 and IFNG production while inducing secretion of transforming growth factor beta, also down-regulates IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. LAIR1 inhibits the differentiation of peripheral blood precursors towards dendritic cells. It also restrains proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-337)
Fournisseur:
ProSci Inc.
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-343)
Fournisseur:
ProSci Inc.
Description:
Human recombinant GCSFR (from HEK293 cells)
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI2415P)
Fournisseur:
ProSci Inc.
Description:
APRIL peptide is used for blocking the activity of APRIL antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-416)
Fournisseur:
ProSci Inc.
Description:
Cathepsin L2 belongs to the Peptidase C1 family. Cathepsin L2 can be autocatalytically convertedto the mature form as a proenzyme in lysosomes at pH=7.0. Cathepsin L2 cannot be expressed in normal mammary gland, colon and peritumoral tissue, but it can be expressed in breast carcinomas and colorectal tissues. These suggeats Cathepsin L2 may play a role in tumor processes. Cathepsin L2 is specifically expressed in the testis, thymus, and corneal epithelium.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-735)
Fournisseur:
ProSci Inc.
Description:
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7421P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the amino terminus of human Bim EL.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7389P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the carboxy terminus of human DAP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7383P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the center of human TRIM24.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7417P)
Fournisseur:
ProSci Inc.
Description:
18 amino acids near the center of La Crosse Virus Nucleocapsid.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5597P)
Fournisseur:
ProSci Inc.
Description:
ESX1 pepide is used for blocking the activity of ESX1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5595P)
Fournisseur:
ProSci Inc.
Description:
CDX2 peptide is used for blocking the activity of CDX2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5993P)
Fournisseur:
ProSci Inc.
Description:
KPNA7 peptide is used for blocking the activity of KPNA7 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-504)
Fournisseur:
ProSci Inc.
Description:
Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) is also known as CD antigen CD306. LAIR2 contains one Ig-like C2-type (immunoglobulin-like) domain. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 / CD306 is thought to be secreted and may help modulate mucosal tolerance.
UOM:
1 * 1 EA
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