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Eiwitten en peptiden


11 184  Er zijn resultaten gevonden.
Eiwitten en peptiden

Proteins are used in routine laboratory procedures such as binding enzymes or coupling peptides to carrier proteins. These kits, mixture solutions, and collagen matrices fulfill a myriad of essential laboratory functions for developing relationships between proteins and other cellular components. The stimulating proteins offered have various amino acid arrangements and functions to fulfill any sample manipulation for testing purposes in any field.


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Itemnummer: (PRSI92-366)

Leverancier:  ProSci Inc.
Omschrijving:   The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerisation and heterodimerisation with ErbB2, resulting in cell signalling, heterodimerisation tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signalling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumours. Several anti-cancer drugs use EGFR as target.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   CTLA-4 (Cytotoxic T-Lymphocyte Antigen 4) is also known as CD152 (Cluster of differentiation 152), is a protein receptor that downregulates the immune system. CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells. The protein contains an extracellular V domain, a transmembrane domain, and a cytoplasmic tail. Alternate splice variants, encoding different isoforms. CTLA4 is similar to the T-cell co-stimulatory protein, CD28, and both molecules bind to CD80 and CD86, also called B7-1 and B7-2 respectively, on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules. Fusion proteins of CTLA4 and antibodies (CTLA4-Ig) have been used in clinical trials for rheumatoid arthritis.
UOM:  1 * 200 µG

Leverancier:  ProSci Inc.
Omschrijving:   Ephrin-B1 (EFNB1) is also known as EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2 (LERK-2), which belongs to the ephrin family. EFNB1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNB1 binds to the receptor tyrosine kinases EPHB1 and EPHA1. EFNB1 binds to, and induce the collapse of, commissural axons/growth cones in vitro. EFNB1 may play a role in constraining the orientation of longitudinally projecting axons. EFNB1 interacts with GRIP1 and GRIP2.
UOM:  1 * 200 µG

Leverancier:  ProSci Inc.
Omschrijving:   Hemoglobin Subunit Zeta (HBZ) is a member of the Globin family. The zeta chain is an alpha-type chain of mammalian embryonic Hemoglobin that is synthesized primarily in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal growth and adult life. The HBZ gene consists of five functional genes and two pseudogenes, the order of genes is 5-zeta-pseudozeta-mu-pseudoalpha-1-alpha-2-alpha-1-theta-1-3.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilises intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   VASH1 peptide is used for blocking the activity of VASH1 antibody.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   Akirin2 peptide is used for blocking the activity of Akirin2 antibody.
UOM:  1 * 50 µG
Itemnummer: (PRSI2245P)

Leverancier:  ProSci Inc.
Omschrijving:   Caspase-13 peptide is used for blocking the activity of caspase-13 antibody.
UOM:  1 * 50 µG
Itemnummer: (PRSI2185P)

Leverancier:  ProSci Inc.
Omschrijving:   ARC peptide is used for blocking the activity of ARC antibody.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   MettL7A peptide is used for blocking the activity of MettL7A antibody.
UOM:  1 * 50 µG
Itemnummer: (PRSI2443P)

Leverancier:  ProSci Inc.
Omschrijving:   PID peptide is used for blocking the activity of PID antibody.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   UHRF1BP1L peptide is used for blocking the activity of UHRF1BP1L antibody.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   SPRYD2 peptide is used for blocking the activity of SPRYD2 antibody.
UOM:  1 * 50 µG

Leverancier:  ProSci Inc.
Omschrijving:   Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
UOM:  1 * 200 µG

Leverancier:  ProSci Inc.
Omschrijving:   Endothelial protein C receptor (PROCR) is also known as Activated protein C receptor (APC receptor), Endothelial cell protein C receptor, CD antigen CD201. PROCR / EPCR / CD201 is a N-glycosylated protein, with a soluble form exists. PROCR is probably released by a metalloprotease. PROCR seems to have the same activity as the membrane-bound form. PROCR / EPCR / CD201 is expressed strongly in the endothelial cells of arteries and veins in heart and lung. PROCR binds activated protein C and enhances protein C activation by the thrombin - thrombomodulin complex. PROCR plays a role in the protein C pathway controlling blood coagulation.
UOM:  1 * 1 EA
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De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het call nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
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