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Eiwitten en peptiden
Itemnummer:
(PRSI91-254)
Leverancier:
ProSci Inc.
Omschrijving:
Haloacid Dehalogenase-Like Hydrolase Domain-Containing Protein 22 (HDHD2) is a member of the HAD-like hydrolase superfamily. HDHD2 includes L-2-Haloacid Dehalogenase, Epoxide Hydrolases and Phosphatases. There are two active sites in HDHD2 - an L-2-Haloacid Dehalogenase and a Carboxylate group. The L-2-Haloacid Dehalogenase active site catalyzes the hydrolytic dehalogenation of D- and L-2-Haloalkanoic Acids, producing L- and D-2-Hydroxyalkanoic Acids.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6403P)
Leverancier:
ProSci Inc.
Omschrijving:
SPRYD2 peptide is used for blocking the activity of SPRYD2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6385P)
Leverancier:
ProSci Inc.
Omschrijving:
GEMC1 peptide is used for blocking the activity of GEMC1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6399P)
Leverancier:
ProSci Inc.
Omschrijving:
CCDC141 peptide is used for blocking the activity of CCDC141 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-368)
Leverancier:
ProSci Inc.
Omschrijving:
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Unlike the precursor forms of other papain family members, the 43 kDa pro-cathepsin L itself is secreted from various cells. Pro-cathepsin L is the major excreted protein of malignantly transformed mouse fibroblasts and is also one of the major acidic cysteine proteases in mammalian cells.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5731P)
Leverancier:
ProSci Inc.
Omschrijving:
APC7 peptide is used for blocking the activity of APC7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5747P)
Leverancier:
ProSci Inc.
Omschrijving:
PIAS4 peptide is used for blocking the activity of PIAS4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6889P)
Leverancier:
ProSci Inc.
Omschrijving:
ABCA7 peptide is used for blocking the activity of ABCA7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-036)
Leverancier:
ProSci Inc.
Omschrijving:
Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. In addition, PRDX4 is probably involved in redox regulation of the cell, regulating the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6461P)
Leverancier:
ProSci Inc.
Omschrijving:
UHRF1BP1L peptide is used for blocking the activity of UHRF1BP1L antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-193)
Leverancier:
ProSci Inc.
Omschrijving:
Calreticulin-3 belongs to the calreticulin family, members of which are calcium binding chaperones localised mainly in the endoplasmic reticulum. It can be divided into a N-terminal globular domain, a proline-rich P-domain forming an elongated arm-like structure and a C-terminal acidic domain. During spermatogenesis process, Calreticulin-3 may act as a lectin-independent chaperone for specific client proteins such as ADAM3. Defects in CALR3 are the cause of familial hypertrophic cardiomyopathy type 19 (CMH19), it is a hereditary heart disorder characterised by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-204)
Leverancier:
ProSci Inc.
Omschrijving:
Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-196)
Leverancier:
ProSci Inc.
Omschrijving:
ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at least SRCAP, DMAP, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. ZNHIT1 may play a role in p53-mediated apoptosis induction.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-198)
Leverancier:
ProSci Inc.
Omschrijving:
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-589)
Leverancier:
ProSci Inc.
Omschrijving:
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. This receptor is very similar to the IL-1 receptor type I and the IL-18 receptor alpha chain in that ST2 also has three extracellular Ig domains and an intracellular Toll domain. ST2 binds IL-33, enhances inflammatory cytokines by activating nuclear factor-κB (NF-κB) and mitogen activated protein (MAP) kinases. ST2 exists as either a membrane bound form (ST2L) or as a soluble form (sST2). ST2L acts as a transmembrane signalling receptor for IL-33 by mediating the effect of IL-33 on the inflammatory process, while sST2 can suppress IL-33 activity.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-590)
Leverancier:
ProSci Inc.
Omschrijving:
FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51（alpha chain) and Beta-2-microglobulin（Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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