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Eiwitten en peptiden
Itemnummer:
(PRSI4351P)
Leverancier:
ProSci Inc.
Omschrijving:
LGP2 peptide is used for blocking the activity of LGP2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4341P)
Leverancier:
ProSci Inc.
Omschrijving:
TEM7 peptide is used for blocking the activity of TEM7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4347P)
Leverancier:
ProSci Inc.
Omschrijving:
MANF peptide is used for blocking the activity of MANF antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4349P)
Leverancier:
ProSci Inc.
Omschrijving:
MANF peptide is used for blocking the activity of MANF antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-373)
Leverancier:
ProSci Inc.
Omschrijving:
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
UOM:
1 * 1 EA
Itemnummer:
(PRSI92-434)
Leverancier:
ProSci Inc.
Omschrijving:
Serpin B9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. Serpin B9 is an inhibitor of the granzyme B/perforin lytic pathway. It is expressed in normal mammary epithelial cells but not in most mammary carcinoma cell lines. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodelling, and apoptosis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5047P)
Leverancier:
ProSci Inc.
Omschrijving:
CDIP peptide is used for blocking the activity of CDIP antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5057P)
Leverancier:
ProSci Inc.
Omschrijving:
FNIP2 peptide is used for blocking the activity of FNIP2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5043P)
Leverancier:
ProSci Inc.
Omschrijving:
TMEM18 peptide is used for blocking the activity of TMEM18 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI96-658)
Leverancier:
ProSci Inc.
Omschrijving:
R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilisation. A putative nuclear localisation signal at the C-terminus may allow some expression in the nucleus.
UOM:
1 * 50 µG
Itemnummer:
(PRSI96-676)
Leverancier:
ProSci Inc.
Omschrijving:
Kit ligand (KITLG) is also known as stem cell factor (SCF), mast cell growth factor (MGF), steel factor (SF), which belongs to the SCF family, and is a widely expressed 28 - 40 kDa type I transmembrane glycoprotein. KITLG is the ligand for the receptor-type protein-tyrosine kinase KIT. SCF / MGF plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG / SCF binding can activate several signaling pathways. KITLG / SF Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG / SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG / SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG / SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol 1, 4, 5 - trisphosphate. KITLG / SCF acts synergistically with other cytokines, probably interleukins.
UOM:
1 * 20 µG
Itemnummer:
(PRSI96-671)
Leverancier:
ProSci Inc.
Omschrijving:
S100 calcium-binding protein P (S100P),a member of the S-100 family, is also known as protein S100-P, migration-inducing gene 9 protein (MIG9) and protein S100-E,which contains two EF-hand domains. As for subunit structure,S100P is homodimer and heterodimer with S100A1. S100P may function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, S100P functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. Furthermore,S100P may stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
UOM:
1 * 1 EA
Itemnummer:
(PRSI96-674)
Leverancier:
ProSci Inc.
Omschrijving:
Scavenger receptor class B member 2 (SCARB2) is also known as Lysosome membrane protein 2 (LIMP2), 85 kDa lysosomal membrane sialoglycoprotein (LGP85), CD36 antigen-like 2 (CD36L2, LIMP2), which belongs to the CD36 family. SCARB2 acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
UOM:
1 * 1 EA
Itemnummer:
(PRSI92-219)
Leverancier:
ProSci Inc.
Omschrijving:
IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.
UOM:
1 * 50 µG
Itemnummer:
(PRSI96-067)
Leverancier:
ProSci Inc.
Omschrijving:
B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
UOM:
1 * 1 EA
Itemnummer:
(PRSI4407P)
Leverancier:
ProSci Inc.
Omschrijving:
IPR1 peptide is used for blocking the activity of IPR1 antibody.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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