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Protéines et Peptides
Numéro de catalogue:
(PRSI91-352)
Fournisseur:
ProSci Inc.
Description:
Signal Regulatory Protein alpha (SIRP alpha) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRP alpha contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRP alpha can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRP alpha acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRP alpha shows adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. SIRP alpha engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis, mast cell activation and dendritic cell activation
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3493P)
Fournisseur:
ProSci Inc.
Description:
Raptor peptide is used for blocking the activity of the Raptor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3477P)
Fournisseur:
ProSci Inc.
Description:
Mcl-1 peptide is used for blocking the activity of Mcl-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-343)
Fournisseur:
ProSci Inc.
Description:
Human recombinant GCSFR (from HEK293 cells)
UOM:
1 * 200 µG
Numéro de catalogue:
(PRSI3623P)
Fournisseur:
ProSci Inc.
Description:
CRMP1 peptide is used for blocking the activity of CRMP1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3609P)
Fournisseur:
ProSci Inc.
Description:
AES peptide is used for blocking the activity of AES antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-516)
Fournisseur:
ProSci Inc.
Description:
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7005P)
Fournisseur:
ProSci Inc.
Description:
ATG2B peptide is used for blocking the activity of ATG2B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-692)
Fournisseur:
ProSci Inc.
Description:
Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endothelium. COL8A1 forms homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 contains one C1q domain and is primarily expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury, in atherosclerosis and in diabetes. COL8A1 may have a role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-686)
Fournisseur:
ProSci Inc.
Description:
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-697)
Fournisseur:
ProSci Inc.
Description:
Ameloblastin (AMBN) is a member of the Ameloblastin family. AMBN is a secreted protein and is specially expressed in ameloblast, localizing to the Tomes processes of secretory ameloblasts and in the sheath space between rod-interrod enamel Mutations of this protein may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. Ameloblastin may play an important role in the formation and mineralization of the enamel matrix. Biochemically, it is classified as an intrinsically disordered protein (IDP). Its biological role remains largely unknown.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7001P)
Fournisseur:
ProSci Inc.
Description:
RGS22 peptide is used for blocking the activity of RGS22 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3517P)
Fournisseur:
ProSci Inc.
Description:
PTEN peptide is used for blocking the activity of the PTEN antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-696)
Fournisseur:
ProSci Inc.
Description:
Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7033P)
Fournisseur:
ProSci Inc.
Description:
SGSM1 peptide is used for blocking the activity of SGSM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3521P)
Fournisseur:
ProSci Inc.
Description:
IRS-1peptide is used for blocking the activity of IRS-1 antibody.
UOM:
1 * 50 µG
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