Imprimer
Votre recherche pour:
11 234 les résultats ont été trouvés
Protéines et Peptides
Numéro de catalogue:
(PRSI40-518)
Fournisseur:
ProSci Inc.
Description:
Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity, which leads to tyrosine phosphorylation. Although HRG1-β1 biological effects is still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant human Heregulin-β1 (HRG1-β1) is a 7.5 kDa polypeptide consisting of only the EGF domain of heregulin-β1 (65 amino acid residues).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI40-521)
Fournisseur:
ProSci Inc.
Description:
Human IL-17A is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant human IL-17A is a 31.0 kDa disulfide-linked homodimer of two 136 amino acid polypeptide chains.
UOM:
1 * 25 µG
Numéro de catalogue:
(PRSI3809P)
Fournisseur:
ProSci Inc.
Description:
TIM-1 peptide is used for blocking activity of TIM-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5389P)
Fournisseur:
ProSci Inc.
Description:
RIPK1 peptide is used for blocking the activity of RIPK1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5385P)
Fournisseur:
ProSci Inc.
Description:
JMJD7 peptide is used for blocking the activity of JMJD7 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4803P)
Fournisseur:
ProSci Inc.
Description:
Akirin2 peptide is used for blocking the activity of Akirin2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6861P)
Fournisseur:
ProSci Inc.
Description:
ZNF687 peptide is used for blocking the activity of ZNF687 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-145)
Fournisseur:
ProSci Inc.
Description:
Myozenin 2 (MYOZ2) is a 264 amino acid protein that belongs to the myozenin family. MYOZ2 binds to Calcineurin, a phosphatase that is involved in calcium-dependent signal transduction in diverse cell types. MYOZ2 is one of the sarcomeric proteins and plays an important role in myofibrillogenesis and the modulation of calcineurin signalling. It may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and plays an important role in the modulation of calcineurin signalling. Defects in MYOZ2 are the cause of familial hypertrophic cardiomyopathy type 16 (CMH16), a hereditary heart disorder.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-188)
Fournisseur:
ProSci Inc.
Description:
Annexin A7 (ANXA7) is a member of the annexin family of calcium-dependent phospholipid binding proteins. Annexin A7 has a unique, highly hydrophobic N-terminal domain and a conserved C-terminal region. The C-terminal region is composed of alternating hydrophobic and hydrophilic segments. Annexin A7 is a calcium/phospholipid-binding protein with diverse properties including voltage-sensitive calcium channel activity and promotes membrane fusion and is also involved in exocytosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-197)
Fournisseur:
ProSci Inc.
Description:
Cytochrome b5 (CYB5A) is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases. CYB5A contains one cytochrome b5 heme-binding domain and has two isoforms produced by alternative splicing. Isoform 1 is a sngle-pass membrane protein. Isoform 2 is located in cytoplasm. The defects in CYB5A can result in type IV hereditary methemoglobinemia.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-006)
Fournisseur:
ProSci Inc.
Description:
TNF alpha is a homotrimer with a subunit molecular mass of 17 kD and plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, autoimmune diseases and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF was found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn’s disease, and rheumatoid arthritis as well as graft-versus-host disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-222)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin Thioesterase OTUB2 belongs to the peptidase C65 family, functions as a hydrolase that can remove conjugated ubiquitin from proteins in vitro, may plays an important regulatory role at the level of protein turnover by preventing degradation. OTUB2 is expressed at higher levels in the brain.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-423)
Fournisseur:
ProSci Inc.
Description:
Junctional Adhesion Molecule A (JAM-A) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. JAM-A contains 2 Ig-like V-type (immunoglobulin-like) domains and Interacts with the ninth PDZ domain. JAM-A is localized to the tight junctions of both epithelial and endothelial cells. JAM-A seems to be involved in epithelial tight junction formation. JAM-A appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM-A, thereby preventing tight junction assembly. JAM-A plays a role in regulating monocyte transmigration involved in regulating integrity of the epithelial barrier. In the case of orthoreovirus infection, JAM-A serves as receptor for the virus.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-422)
Fournisseur:
ProSci Inc.
Description:
Human Erythroid Membrane-Associated Protein (ERMAP) is a cell surface transmembrane protein that belongs to the immunoglobulin superfamily. It is hghly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen. ERMAP contains 1 B30.2/SPRY domain and 1 Ig-like V-type (immunoglobulin-like) domain. It may serve as an erythroid cell receptor, possibly as a mediator of cell adhesion. ERMAP is responsible for the Scianna/Radin blood group system. Two transcript variants encoding the same protein have been found for this gene ERMAP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-429)
Fournisseur:
ProSci Inc.
Description:
Human Glycoprotein A33 (GPA33) is a single-pass type I membrane protein, belongs to the CTX family of cell adhesion molecular within the immunoglobulin family, can be expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 consists of one Ig-like C2-type domain and one Ig-like V-type domain. The predicted mature protein includes a single transmembrane domain, a extracellular region and a intracellular tail. Intracellular traffic and recycling to the cell surface appear to play an important role in GPA33 function and to have an influence on its surface density superseding translation regulation. GPA33 has become a promising target of immunologic therapy strategies. GPA33 may also play a important role in cell-cell recognition and signaling.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-329)
Fournisseur:
ProSci Inc.
Description:
Follistatin-related protein 1 (FSTL1) is also known as Follistatin-like protein 1 (FRP). FSTL1 is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain and one VWFC domain. FSTL1 is overexpressed in synovial tissues from rheumatoid arthritis. Follistatin-like protein 1 / FSTL1 may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 binds heparin.
UOM:
1 * 1 EA
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||
Vue liste
