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Eiwitten en peptiden
Itemnummer:
(PRSI4479P)
Leverancier:
ProSci Inc.
Omschrijving:
Slitrk6 peptide is used for blocking the activity of Slitrk6 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-283)
Leverancier:
ProSci Inc.
Omschrijving:
Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-289)
Leverancier:
ProSci Inc.
Omschrijving:
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5581P)
Leverancier:
ProSci Inc.
Omschrijving:
POU5F1 peptide is used for blocking the activity of POU5F1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5583P)
Leverancier:
ProSci Inc.
Omschrijving:
SOX2 peptide is used for blocking the activity of SOX2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI2233P)
Leverancier:
ProSci Inc.
Omschrijving:
Survivin peptide is used for blocking the activity of Survivin antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI2219P)
Leverancier:
ProSci Inc.
Omschrijving:
Acinus peptide is used for blocking the activity of Acinus antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-083)
Leverancier:
ProSci Inc.
Omschrijving:
Sonic Hedgehog Homolog (SHH) belongs to a three-protein family called hedgehog. The other two family members are Indian Hedgehog (IHH) and Desert Hedgehog (DHH). Hedgehog proteins are key signaling molecules in embryonic development. SHH is expressed in various embryonic tissues and plays critical roles in regulating the patterning of many systems, such as limbs and brain. SHH also plays an important role in adult, including the division of adult stem cells and the development of certain cancers and other diseases. Human SHH is expressed as a 45kDa precursor, and undergoes a series of processing during secretion. After the removal of the signal peptide, a protease within the C-terminal domain catalyzes the cleavage of SHH into a 20 kDa N-terminal signaling domain (SHH-N) and a 25 kDa C-terminal domain (SHH-C). SHH-N has the “all signaling” capability. SHH-N binds to the 12 pass transmembrane protein Patched (Ptc) on cell surface, which releases the repression of the activity of Smoothened (Smo), a G-protein coupled receptor, by Ptc.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-637)
Leverancier:
ProSci Inc.
Omschrijving:
Protein S100-A9 (also MRP14 and calgranulin B)is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-087)
Leverancier:
ProSci Inc.
Omschrijving:
Bcl-2-Like Protein 1 (BCL2L1) is a member of the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a mitochondrial membrane protein. BCL2L1 contains four motifs, BH1, BH2 and BH4. The BH4 motif is required for anti-apoptotic activity. The BH1 and BH2 motifs are required for both heterodimerization with other Bcl-2 family members and for repression of cell death. BCL2L1 regulates cell death by blocking the voltage-dependent anion channnel (VDAC) and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. In addition, BCL2L1 promotes apoptosis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-086)
Leverancier:
ProSci Inc.
Omschrijving:
Bcl-2-Related Protein A1 (BCL2A1) is a member of of the BCL-2 protein family which act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. BCL2A1 is a cytoplasm protein and interacts directly with BAK1, BID, BMF and BBC3. BCL2A1 is induced by phorbol ester and inflammatory cytokines, such as TNF or IL1B/interleukin-1 beta, but not by growth factors. BCL2A1 is invovled in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-139)
Leverancier:
ProSci Inc.
Omschrijving:
DLK1 (Protein delta homolog 1; Preadipocyte factor 1; Pref-1) is a regulator of adipocyte differentiation found in serum and urine. DLK1 might be a decoy ligand. Serum or plasma levels of soluble DLK1 affect negatively or positively adipogenesis and control mesenchymal cell fate. DLK1 is frequently upregulated in myelodysplastic syndrome (MDS) patients compared to non-leukemic individuals.
UOM:
1 * 1 EA
Itemnummer:
(PRSI4827P)
Leverancier:
ProSci Inc.
Omschrijving:
Integrin alpha 4 peptide is used for blocking the activity of integrin alpha 4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4811P)
Leverancier:
ProSci Inc.
Omschrijving:
OTUD5 peptide is used for blocking the activity of OTUD5 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6871P)
Leverancier:
ProSci Inc.
Omschrijving:
FCHO2 peptide is used for blocking the activity of FCHO2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3783P)
Leverancier:
ProSci Inc.
Omschrijving:
GAPDH peptide is used for blocking the activity of GAPDH antibody.
UOM:
1 * 50 µG
Bel voor prijs
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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