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Eiwitten en peptiden
Itemnummer:
(PRSI91-350)
Leverancier:
ProSci Inc.
Omschrijving:
The Urokinase Type Plasminogen Activator (uPA) receptor (uPAR) is a widely expressed receptor for urokinase plasminogen activator (uPA) and pro-uPA. uPAR / CD87 is a highly glycosylated, 55-60kDa integral membrane protein linked to the plasma membrane by a glycosylphosphatidylinositol (GPI) anchor. uPAR is expressed by T-cells, NK cells, monocytes, and neutrophils as well as non-hematopoietic cells that include vascular endothelial cells, fibroblasts, smooth muscle cells, keratinocytes, placental trophoblasts, hepatocytes, and a wide variety of tumor cells (including breast, colon, and prostate carcinoma, melanoma). It plays a critical role in the regulation of cell-surface plasminogen activation in physiological and pathological conditions, and it is also involved in cellular adhesion, the transmission of extracellular signals across the plasma membrane and the subsequent regulation of gene expression. uPAR has been implicated in several biological processes including angiogenesis, monocyte migration, cancer metastasis, trophoblast implantation, and wound healing. Human uPAR is encoded as a 313 amino acid residue polypeptide, excluding a 22 residue signal peptide and shows 60-70% similarity with the murine uPAR amino acid sequence although binding of uPA to uPAR shows strong species specificity.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6599P)
Leverancier:
ProSci Inc.
Omschrijving:
LEMD1 peptide is used for blocking the activity of LEMD1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6611P)
Leverancier:
ProSci Inc.
Omschrijving:
ZGPAT peptide is used for blocking the activity of ZGPAT antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-978)
Leverancier:
ProSci Inc.
Omschrijving:
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-971)
Leverancier:
ProSci Inc.
Omschrijving:
Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is involved in multiple basic cellular functions. The expression of PBLD can be increased in several disease processes, including insulin resistance, folate deficiency and hypotension.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5611P)
Leverancier:
ProSci Inc.
Omschrijving:
ZSCAN4 pepide is used for blocking the activity of ZSCAN4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5607P)
Leverancier:
ProSci Inc.
Omschrijving:
RSRC1 pepide is used for blocking the activity of RSRC1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5621P)
Leverancier:
ProSci Inc.
Omschrijving:
LZTR1 pepide is used for blocking the activity of LZTR1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-521)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL2 shares 56% and 73% aa sequence identity with human and rat IL2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma delta T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL2 may be a key cytokine in the natural suppression of autoimmunity.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3485P)
Leverancier:
ProSci Inc.
Omschrijving:
TOR peptide is used for blocking the activity of TOR antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3479P)
Leverancier:
ProSci Inc.
Omschrijving:
Mcl-1 peptide is used for blocking the activity of Mcl-1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-166)
Leverancier:
ProSci Inc.
Omschrijving:
Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain, with highest levels found in cortex and striatum, and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition, UBE2K is involved in Alzheimer's disease, Huntington's disease and antigen processing through its interaction with huntingtin, and MHC-heavy chain proteins.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-725)
Leverancier:
ProSci Inc.
Omschrijving:
Follitropin Subunit beta (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit beta family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common alpha chain and an unique beta chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD).
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-723)
Leverancier:
ProSci Inc.
Omschrijving:
Uroplakin-2 is a single-pass type I membrane protein that belongs to the uroplakin-2 family. Uroplakin-2 is a component of the asymmetric unit membrane (AUM) and expressed in the ureter, a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. Uroplakin-2 forms heterodimer with UPK1A that is necessary for exiting out of the endoplasmic reticulum (ER). Uroplakin-2 may play an important role in regulating the assembly of the AUM. AUM is believed to strengthen the urothelium by preventing cell rupture during bladder distention.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-738)
Leverancier:
ProSci Inc.
Omschrijving:
CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.
UOM:
1 * 50 µG
Itemnummer:
(PRSI7379P)
Leverancier:
ProSci Inc.
Omschrijving:
19 amino acids near the center of human B-raf.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
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