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Eiwitten en peptiden
Itemnummer:
(PRSI1117P)
Leverancier:
ProSci Inc.
Omschrijving:
RAIDD peptide is used for blocking the activity of RAIDD antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI1135P)
Leverancier:
ProSci Inc.
Omschrijving:
GFR alpha 2 peptide is used for blocking the activity of GFR alpha 2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI1129P)
Leverancier:
ProSci Inc.
Omschrijving:
NIK peptide is used for blocking the activity of NIK antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-221)
Leverancier:
ProSci Inc.
Omschrijving:
Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-213)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1/ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-224)
Leverancier:
ProSci Inc.
Omschrijving:
Platelet-Activating Factor Acetylhydrolase IB Subunit beta (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Cytosolic PAF-AH IB is formed of three subunits of 45 kDa (alpha), 30 kDa (beta) and 29 kDa (gamma), PAFAHB is a catalytic subunit. PAFAHB inactivates PAF by removing the acetyl group at the sn-2 position.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3039P)
Leverancier:
ProSci Inc.
Omschrijving:
AATF peptide is used for blocking the activity of AATF antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6755P)
Leverancier:
ProSci Inc.
Omschrijving:
TSHZ1 peptide is used for blocking the activity of TSHZ1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6761P)
Leverancier:
ProSci Inc.
Omschrijving:
FOXRED2 peptide is used for blocking the activity of FOXRED2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6753P)
Leverancier:
ProSci Inc.
Omschrijving:
NKX2-8 peptide is used for blocking the activity of NKX2-8 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI40-595)
Leverancier:
ProSci Inc.
Omschrijving:
The IGFs are mitogenic polypeptide growth factors that stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGFs are predominantly produced by the liver, although a variety of tissues produce the IGFs at distinctive times. The IGFs belong to the Insulin gene family, which also contains insulin and relaxin. The IGFs are similar by structure and function to insulin, but have a much higher growth-promoting activity than insulin. IGF-II expression is influenced by placenta lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), but, IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contain N-terminal and C-terminal propeptide regions. Recombinant human IGF-I and IGF-II are globular proteins containing 70 and 67 amino acids, respectively, and 3 intra-molecular disulfide bonds.
UOM:
1 * 1 EA
Itemnummer:
(PRSI40-597)
Leverancier:
ProSci Inc.
Omschrijving:
IL-16 was initially identified as a chemotactic cytokine (1), but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases (2). The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4 (3,4). Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation (5) and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders (6). At least two isoforms of IL-16 are known to exist; the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus (7). This recombinant protein fragment is derrived from this longer isoform.
UOM:
1 * 1 EA
Itemnummer:
(PRSI96-343)
Leverancier:
ProSci Inc.
Omschrijving:
Human recombinant GCSFR (from HEK293 cells)
UOM:
1 * 200 µG
Itemnummer:
(PRSI91-143)
Leverancier:
ProSci Inc.
Omschrijving:
Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-142)
Leverancier:
ProSci Inc.
Omschrijving:
Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. In addition, inhibition of PPP1R14A also enhances contraction of smooth muscle in the absence of increment of intracellular Ca2+ concentration.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-675)
Leverancier:
ProSci Inc.
Omschrijving:
Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold). GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, but produce the same peptide hormone.
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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