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Eiwitten en peptiden
Itemnummer:
(PRSI3985P)
Leverancier:
ProSci Inc.
Omschrijving:
Nicastrin peptide is used for blocking activity of nicastrin antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3987P)
Leverancier:
ProSci Inc.
Omschrijving:
LKB1 peptide is used for blocking the activity of LKB1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI2223P)
Leverancier:
ProSci Inc.
Omschrijving:
APRIL peptide is used for blocking the activity of APRIL antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5493P)
Leverancier:
ProSci Inc.
Omschrijving:
SIPA1L2 peptide is used for blocking the activity of SIPA1L1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3165P)
Leverancier:
ProSci Inc.
Omschrijving:
Bcl-G peptide is used for blocking the activity of Anit-Bcl-G antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-481)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts numerous effects on various hematopoietic cell types. On B cells, IL-4 promotes immunoglobulin class switching to IgE and IgG1 isotypes and upregulates MHC class II and CD23 expression. IL-4 promotes survival, growth and differentiation of both T and B lymphocytes, mast cells and endothelial cells. In addition, IL-4 inhibits the production of TNF, IL-1 and IL-6 by macrophages.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-256)
Leverancier:
ProSci Inc.
Omschrijving:
Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-254)
Leverancier:
ProSci Inc.
Omschrijving:
Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognises motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
UOM:
1 * 50 µG
Itemnummer:
(PRSI3025P)
Leverancier:
ProSci Inc.
Omschrijving:
ARTS peptide is used for blocking the activity of ARTS antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3029P)
Leverancier:
ProSci Inc.
Omschrijving:
Bmf peptide is used for blocking the activity of Bmf antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI3073P)
Leverancier:
ProSci Inc.
Omschrijving:
PAK6 peptide is used for blocking activity of PAK6 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-693)
Leverancier:
ProSci Inc.
Omschrijving:
Tumour necrosis factor receptor superfamily member 1A (TNFRSF1A) is a member of the tumour necrosis factor receptor superfamily. TNFRSF1A is one of the major receptors for the tumour necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumour necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-438)
Leverancier:
ProSci Inc.
Omschrijving:
Regenerating protein 2 (Reg2) also known as Lithostathine 2, pancreatic thread protein (PTP2) and pancreatic stone protein 2 (PSP2), is a member of the Reg family of proteins. These small, secreted proteins have been implicated in a range of physiological processes including acting as acute phase reactants, lectins, survival/growth factors for insulin-producing pancreatic beta-cells, neural cells, and epithelial cells of the digestive system. Studies also indicate a role for Reg family members in tumour formation and indicate their potential for use as biomarkers of carcinogenesis. Mouse Reg2 is expressed in regenerating islets and normal exocrine pancreas. Reg2 also stimulates the growth of pancreatic beta cells. Mouse Reg2 belongs to the type II subclass of the Reg family and is the only subclass II Reg protein described.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-719)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-1 receptor type 2 (IL1R2) belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1 receptor type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. IL1R2 is non-signalling receptor forIL1A, IL1B and IL1RN, reduces IL1B activities. IL1R2 serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signalling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4339P)
Leverancier:
ProSci Inc.
Omschrijving:
TEM7 peptide is used for blocking the activity of TEM7 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-450)
Leverancier:
ProSci Inc.
Omschrijving:
Vascular endothelial growth factor D (VEGF-D) is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. It is highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas. VEGF-D is growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. It may function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. It undergoes a complex proteolytic maturation, generating multiple processed forms that bind and activate VEGFR-2 and VEGFR-3 receptors.
UOM:
1 * 50 µG
Bel voor prijs
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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