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ENZO LIFE SCIENCES
Numéro de catalogue:
(ENZOALX210340C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOBPDABS058081)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Anti-GCG Mouse Monoclonal Antibody [clone: 8]
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOADI905776100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Cyclins are a family of proteins which function as the regulatory subunits of cyclin/cyclin-dependent kinase (Cdk) holoenzymes, mediating entry into and progression through the cell cycle. Each cyclin is expressed in a temporal fashion during the cell cycle, partnering with a specific Cdk to activate its protein kinase activity. The most well defined mitotic cyclins are: cyclin D, which partners with cdks 4 and 6 during early G1 phase; cyclin E, which activates Cdk2 in the G1 to S phase transition; cyclin A, which utilizes Cdks 1 and 2 during progression through S phase and into G2; and cyclin B, which activates Cdk1 in M-phase promotion.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADI905813100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The octapeptide circulatory hormone Angiotensin II is a critical regulator of cardiovascular homeostasis formed in blood, with dual function in tissues of the brain, kidney, heart, and vasculature as an autocrine/paracrine growth hormone. The actions of angiotensin II are mediated by type one (AT1) and type two (AT2) angiotensin II receptors, members of the seven-transmembrane Gprotein coupled receptor (GPCR) family. AT1 receptors couple predominantly with Gq/11 alpha subunits, and signal through phospholipases C, D, and A2, inositol phosphates, and calcium channels, as well as a variety of serine/threonine and tyrosine kinases. AT1 expression is greatest in vascular smooth muscle, liver, kidney, adrenal cortex, brain, and lung, and is primarily responsible for the physiological effects of angiotensin II, including regulation of arterial blood pressure, electrolyte and water balance, thirst, hormone secretion, and renal function. The AT2 receptor displays approximately 30% identity to the AT1 receptor, and is highly expressed during embryonic development. AT2 expression in adult tissue is limited to the adrenal medulla, brain, and reproductive tissues, but is upregulated in injured tissue following myocardial infarction, vascular injury, and wound healing. AT2 receptor signaling is not dependent on G-protein coupling or receptor phosphorylation, although coupling to Gia2 and Gia3 alpha subunits occurs in some tissues. AT2 activation can stimulate tyrosine and serine/threonine phosphatases through activation of nitric oxide and cGMP, and appears to counteract the stimulatory effects of AT1 receptor and growth factor receptor signaling.
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
AMPA/kainate receptor antagonist
Fournisseur:
ENZO LIFE SCIENCES
Description:
Okadaic acid potassium salt
Numéro de catalogue:
(ENZOALX350102M100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Vindoline ≥90% (base substance sèche)
UOM:
1 * 100 mg
New Product
Numéro de catalogue:
(ENZOALX350109MC05)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Antibiotic. Inhibitor of NF-κB activation by preventing the phosphorylation of IκB protein and thereby interrupts the signalling pathway. Strongly inhibits the expression of several NF-κB dependent pro-inflammatory genes.
UOM:
1 * 0,5 mg
New Product
Numéro de catalogue:
(ENZOALX350066M100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Na⁺/K⁺ ATPase inhibitor
UOM:
1 * 100 mg
New Product
Numéro de catalogue:
(ENZOBMLAK1710001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Lipid peroxidation is a well-established mechanism of cellular injury in both plants and animals, and is used as an indicator of oxidative stress in cells and tissues. Lipid peroxides, derived from polyunsaturated fatty acids, are unstable and decompose to form a complex series of compounds. These include reactive aldehydes, of which the most abundant is malondialdehyde (MDA). Therefore, measurement of malondialdehyde is widely used as an indicator of lipid peroxidation. Increased levels of lipid peroxidation products have been associated with a variety of chronic diseases in both humans and model systems.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOBMLAK4170001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
A QuantiZyme™ Assay System. The MMP-14 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay sytem designed to screen for inhibitors of matrix metalloproteinase-14 (MMP-14, membrane-type matrix metalloproteinase 1, MT1-MMP) using a quenched fluorogenic peptide: OmniMMP™ fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(ENZOBMLA2490500)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inosine-5'-monophosphate dehydrogenase inhibitor
UOM:
1 * 500 mg
New Product
Numéro de catalogue:
(ENZOBMLAK1270001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Based on the dye cresyl violet and the cathepsin L PheArg peptide recognition sequence, this kit allows the detection of cathepsin L activity in living cells by fluorescence microscopy.
UOM:
1 * 1 KIT
New Product
Numéro de catalogue:
(ENZOALX2018500020)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E. coli</i>. Human Ang-1 (angiopoietin-1) is a single, non-glycosylated polypeptide chain containing 480 amino acids (20 to 498)
UOM:
1 * 20 µG
New Product
Numéro de catalogue:
(ENZOALX202072M001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Isolated from rabbit liver. Mixture of MT isoforms. Contains mainly MT-1a and MT-2e and a minor portion of MT-2d.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(ENZOBMLP1520001)
Fournisseur:
ENZO LIFE SCIENCES
Description:
This peptide sequence, RRApTVA, has been found to be an excellent substrate for both PP2A and PP2C phosphatases.
UOM:
1 * 1 mg
New Product
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