ENZO LIFE SCIENCES
Fournisseur:
ENZO LIFE SCIENCES
Description:
LXR ligand.
Numéro de catalogue:
(ENZOBMLGR2480050)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Estrogen receptor β activator.
UOM:
1 * 50 mg
New Product
Numéro de catalogue:
(ENZOBMLZW86550005)
Fournisseur:
ENZO LIFE SCIENCES
Description:
A ketoaldehyde. An excellent inhibitor of the chymotrypsin-like activity of the proteasome and serine and cysteine proteases in general.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(ENZOBMLVR1020025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Endogenous TRPV1 agonist (Ki=36nM, EC50=36nM) with weak affinity for rat CB1 receptor (Ki=1.6µM). Potent inhibitor of 5-lipoxygenase (IC50=7.5nM) and of early and late events in TCR mediated T cell activation. Inhibits NF-κB dependent transcriptional activity without affecting either degradation of the cytoplasmic NF-κB inhibitory protein, IκBα, or DNA binding activity.
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(ENZOBMLZW91700500)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Inhibits the trypsin-like, chymotrypsin-like and caspase-like (PGPH) activity in isolated proteasomes and living cells by covalent modification of the amino-terminal threonine of the catalytically active beta subunits. The vinyl sulfone acts as a Michael acceptor for soft nucleophiles such as thiols, leading to the formation of a covalent bond, while being resistant to attack by free thiols, which can cause inactivation of other classes of protease inhibitors.
UOM:
1 * 500 µG
New Product
Numéro de catalogue:
(ENZOBMLRA1020100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Prostanoid receptor ligand.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOBMLPW92500025)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Mouse, Isotype: IgG1
UOM:
1 * 25 µl
New Product
Numéro de catalogue:
(ENZOENZ53007C200)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Mixture of fluorescent dyes for detection of lysosomes, mitochondria and nucleic acids
UOM:
1 * 200 µl
New Product
Numéro de catalogue:
(ENZOENZ52501)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Thiol dye
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(ENZOENZ52154)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Chloride dye
UOM:
1 * 10 mg
New Product
Numéro de catalogue:
(ENZOENZ52306)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Mitochondria dye
UOM:
1 * 25 mg
New Product
Numéro de catalogue:
(ENZOALX805088C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
CEA-related cell adhesion molecule 8 (CEACAM8) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosylphosphatidylinositol (GPI)-linked glycoprotein with a molecular mass of of 95kD and is expressed in cells of the granulocyte-lineage. It is expressed in neutrophils and eosinophils and is characterized as a granulocyte-specific activation antigen. Therefore CEACAM8 could serve as a marker for granulocyte activities. Like all members of the CEA family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like A and B domains.
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Produced in <i>E.coli</i>.
Numéro de catalogue:
(ENZOADIKAMCC220E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
DNA-topoisomerase II, also known as Topo II or Top 2, is a multifunctional nuclear enzyme required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities because of its ability to alter DNA supercoiling. In mammalian cells, Topo II consists of two isozymes, Topo II-alpha (170kDa) and Topo II-beta (180kDa) and expression and localization of each isoform are distinct and stage specific during the cell cycle. Topo II-beta is expressed constitutively throughout the cell cycle, whereas the expression of Topo II-alpha is cell cycle-regulated, peaking in G2 to M phase and declining to a minimal level at the end of M phase. DNA-topoisomerase II is the target of some of the most active drugs used in chemotherapy and has been shown to have a critical role in neural development.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADIKAMCC101E)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOADI905749100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
The cannabinoid receptors CB1 and CB2 are GPCRs named for their signaling function in response to cannabinoid drugs such as Delta9-tetrahydrocannabinol (Delta9-THC). In addition to Delta9-THC and its synthetic analogs, CB1 and CB2 receptors are bound by endogenous eicosanoid ligands (e.g. anandamide), and signal via Gi/o alpha subunits to regulate adenylyl cyclase activity (generally inhibitory), ion channel activation, intracellular Ca2+ levels, nitric oxide synthase activation, and immediate early gene expression. CB1 and CB2 signals in turn regulate neurological and immunological functions such as inhibition of neurotransmitter release and immune cell migration, antigen processing, and cytokine production.
UOM:
1 * 1 EA
New Product
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