Imprimer
Votre recherche pour:
11 238 les résultats ont été trouvés
Protéines et Peptides
Numéro de catalogue:
(PRSI6569P)
Fournisseur:
ProSci Inc.
Description:
PIWI-L2 peptide is used for blocking the activity of PIWI-L2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-105)
Fournisseur:
ProSci Inc.
Description:
FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-112)
Fournisseur:
ProSci Inc.
Description:
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4405P)
Fournisseur:
ProSci Inc.
Description:
FEZ2 peptide is used for blocking the activity of FEZ2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4411P)
Fournisseur:
ProSci Inc.
Description:
SAPAP3 peptide is used for blocking the activity of SAPAP3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-723)
Fournisseur:
ProSci Inc.
Description:
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory protein CD28 since both of the molecules bind to CD80 and CD86 on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA4. Genetic variations of CTLA4 have been associated with susceptibility to systemic lupus erythematosus(SLE), Gravesdisease(GRD), Celiac disease type3(CELIAC3) and Hepatitis B virus infection(HBVinfection).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-721)
Fournisseur:
ProSci Inc.
Description:
Mouse Interleukin 1 receptor, type II (IL1R2) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. IL-1R2 structurally consisting of a ligand binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain. It is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. Mouse IL1RII shares 59% amino acid sequence homology with human IL1 RII in their extracellular domains. The pleiotropic cytokine IL1 is produced to regulate development and maintenance of the inflammatory responses, and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signalling, whereas the IL-1R2 has no signalling property and acts as a decoy for IL-1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6039P)
Fournisseur:
ProSci Inc.
Description:
APBA2 peptide is used for blocking the activity of APBA2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6033P)
Fournisseur:
ProSci Inc.
Description:
PIWI-L3 peptide is used for blocking the activity of PIWI-L3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3777P)
Fournisseur:
ProSci Inc.
Description:
Beta-actin peptide is used for blocking the activity of beta-actin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7425P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the carboxy terminus of FGFR3.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5761P)
Fournisseur:
ProSci Inc.
Description:
RBBP8 peptide is used for blocking the activity of RBBP8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6133P)
Fournisseur:
ProSci Inc.
Description:
ZMYM1 peptide is used for blocking the activity of ZMYM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6137P)
Fournisseur:
ProSci Inc.
Description:
ZMYM3 peptide is used for blocking the activity of ZMYM3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-564)
Fournisseur:
ProSci Inc.
Description:
Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumour angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25 aa signal peptide. The mature chain of CHL2 protein contains two potential N-linked glycosylation sites, one putative NLS and three 63 aa cysteine-rich von Willebrand type C repeats (CRs). CHL2 gene is weakly expressed in the liver and kidney, partly expressed in the connective tissues of reproductive organs such as ligaments of the ovary and oviduct in females, and of testis, epididymis and certain male accessory sex glands in males. Recombinant mCHL2 protein interacted directly with five BMPs and one GDF thereby inhibiting, in vitro, several BMP/GDF-dependent processes including, osteogenic differentiation of C2C12 mesenchymal progenitor cells by several BMPs, ATDC5 embryonal carcinoma cells by GDF5 and BMP4-dependent lymphohematopoietic (CD34+CD31hi and CD34+CD31lo) progenitor cell development from ES cells. CHL2 may inhibits BMPs activity by blocking their interaction with their receptors, and has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. Also, it may play a role during myoblast and osteoblast differentiation, and maturation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-001)
Fournisseur:
ProSci Inc.
Description:
As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated EGF receptor/EGFR and PDGF receptors via its SH2 domain, stimulating GTP binding to Ras, which in turn activates MAPK and other signaling pathway.It also associates to other cellular Tyr-phosphorylated proteins such as SIT1, IRS1, IRS4, SHC and LNK. probably via the concerted action of both its SH2 and SH3 domains.
UOM:
1 * 50 µG
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||
Vue liste
