Protéines et Peptides
Numéro de catalogue:
(PRSI92-400)
Fournisseur:
ProSci Inc.
Description:
Mouse tumour necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumour suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signalling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-433)
Fournisseur:
ProSci Inc.
Description:
Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-605)
Fournisseur:
ProSci Inc.
Description:
Mouse HLA class II histocompatibility antigen gamma chain (CD74), is a single-pass type II membrane protein that in humans is encoded by the CD74 gene. It contains 1 thyroglobulin type-1 domain. CD74 Plays a critical role in MHC class II antigen processing by stabilising peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4921P)
Fournisseur:
ProSci Inc.
Description:
JPH3 peptide is used for blocking the activity of JPH3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3607P)
Fournisseur:
ProSci Inc.
Description:
AES peptide is used for blocking the activity of AES antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5011P)
Fournisseur:
ProSci Inc.
Description:
PDCD5 peptide is used for blocking the activity of PDCD5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4997P)
Fournisseur:
ProSci Inc.
Description:
OCC-1 peptide is used for blocking the activity of OCC-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6461P)
Fournisseur:
ProSci Inc.
Description:
UHRF1BP1L peptide is used for blocking the activity of UHRF1BP1L antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6999P)
Fournisseur:
ProSci Inc.
Description:
BCAR3 peptide is used for blocking the activity of BCAR3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4123P)
Fournisseur:
ProSci Inc.
Description:
STIM2 peptide is used for blocking the activity of STIM2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4107P)
Fournisseur:
ProSci Inc.
Description:
NPAS3 peptide is used for blocking the activity of NPAS3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-355)
Fournisseur:
ProSci Inc.
Description:
Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI92-513)
Fournisseur:
ProSci Inc.
Description:
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP (159 aa) and sfTSLP (63 aa) produced by alternative splicing . lfTSLP (159aa) is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral mucosa, skin and in salivary glands. In aa sequence level, Human TSLP displays about 43% identity with mouse TSLP. Thymic stromal lymphopoietin (TSLP) is a cytokine that functions mainly on myeloid cells; it induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells . TSLP has proliferative effects on the myeloid cell line and may initiate asthma or atopic dermatitis responses by directly activating mast cells . TSLP signals cells via the interleukin-7 receptor- alpha chain (IL-7R alpha), shared with IL-7, together with the TSLP receptor (TSLPR) subunit. Recent studies indicate that TSLP and its receptor are novel therapeutic targets for rheumatoid arthritis , for increased intraarticular TSLP concentrations in patients has caused chemotaxis and activation of arthritogenic T cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5233P)
Fournisseur:
ProSci Inc.
Description:
Swine H1N1 Hemagglutinin peptide is meant to be used as a positive control in ELISA applications to detect Swine-Origin Influenza A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5237P)
Fournisseur:
ProSci Inc.
Description:
Swine H1N1 Hemagglutinin peptide is meant to be used as a positive control in ELISA applications to detect Swine-Origin Influenza A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-334)
Fournisseur:
ProSci Inc.
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
UOM:
1 * 50 µG
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l' est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l' est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||