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Eiwitten en peptiden
Itemnummer:
(PRSI91-274)
Leverancier:
ProSci Inc.
Omschrijving:
Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6053P)
Leverancier:
ProSci Inc.
Omschrijving:
SYNPO2L peptide is used for blocking the activity of SYNPO2L antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6065P)
Leverancier:
ProSci Inc.
Omschrijving:
ZNF521 peptide is used for blocking the activity of ZNF521 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4485P)
Leverancier:
ProSci Inc.
Omschrijving:
SIRT2 peptide is used for blocking the activity of Sirt2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5575P)
Leverancier:
ProSci Inc.
Omschrijving:
REEP4 peptide is used for blocking the activity of REEP4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI40-598)
Leverancier:
ProSci Inc.
Omschrijving:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1β is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues.
UOM:
1 * 1 EA
Itemnummer:
(PRSI4051P)
Leverancier:
ProSci Inc.
Omschrijving:
TIGAR peptide is used for blocking the activity of TIGAR antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI92-072)
Leverancier:
ProSci Inc.
Omschrijving:
Serum Amyloid A-4 Protein (SAA4) is a member of the SAA family. SAA proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. SAA4 is constitutively expressed only in humans and mice. Its physiological function is unknown. SAA4 functions as a major acute phase reactant. SAA4 mRNA and protein occurrence in macrophage derived foam cells of coronary and carotid arteries implied a specific role of human SAA4 during inflammation including atherosclerosis.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-226)
Leverancier:
ProSci Inc.
Omschrijving:
DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-232)
Leverancier:
ProSci Inc.
Omschrijving:
MultimericCD40L™ is a high activity construct in which two trimeric CD40 ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the natural membrane-assisted aggregation of CD40L in vivo. It provides a simple and equally potent alternative to CD40L+enhancer combinations. MultimericCD40L™ has shown to suppress alum-induced IL-1beta release and caspase-1 activation in a dose-, CD40- and time dependent manner, without affecting BMDM (Bone marrow-derived macrophages) viability. It also effectively suppressed the inflammasome function triggered by NLRP3 activators. The secretion of caspase-1 independent inflammatory mediators has been shown to be unaltered or even enhanced.
UOM:
1 * 1 EA
Itemnummer:
(PRSI92-630)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulphide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4805P)
Leverancier:
ProSci Inc.
Omschrijving:
Akirin2 peptide is used for blocking the activity of Akirin2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4813P)
Leverancier:
ProSci Inc.
Omschrijving:
CNOT4 peptide is used for blocking the activity of CNOT4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4817P)
Leverancier:
ProSci Inc.
Omschrijving:
ZBRK1 peptide is used for blocking the activity of ZBRK1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5797P)
Leverancier:
ProSci Inc.
Omschrijving:
ATG9B peptide is used for blocking the activity of ATG9B antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI91-119)
Leverancier:
ProSci Inc.
Omschrijving:
Fatty Acid-Binding Protein 4 (FABP4) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP4 is expressed in a differentiation-dependent fashion in adipocytes and is a critical gene in the regulation of the biological function of these cells. FABP4 is thought to participate in Lipid transport protein in adipocytes. FABP4 binds to the long chain fatty acids and retinoic acid, delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. FABP4 modulates inflammatory responses and cholesterol ester accumulation. FABP4 is a plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.
UOM:
1 * 50 µG
Bel voor prijs
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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