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Protéines et Peptides
Numéro de catalogue:
(PRSI7101P)
Fournisseur:
ProSci Inc.
Description:
FRL1 Peptide is used for blocking the activity of FRL1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3687P)
Fournisseur:
ProSci Inc.
Description:
XBP-1 peptide is used for blocking the activity of XBP-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3763P)
Fournisseur:
ProSci Inc.
Description:
LSD1 peptide is used for blocking the activity of LSD1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3737P)
Fournisseur:
ProSci Inc.
Description:
TLR9 peptide is used for blocking the activity of TLR9 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3749P)
Fournisseur:
ProSci Inc.
Description:
IL-32 peptide is used for blocking the activity of IL-32 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3743P)
Fournisseur:
ProSci Inc.
Description:
TOLLIP peptide is used for blocking the activity of TOLLIP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-638)
Fournisseur:
ProSci Inc.
Description:
S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6173P)
Fournisseur:
ProSci Inc.
Description:
LRRTM4 peptide is used for blocking the activity of LRRTM4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-322)
Fournisseur:
ProSci Inc.
Description:
Fibronectin Leucine Rich Transmembrane protein 2 (FLRT2) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins: FLRT1, FLRT2 and FLRT3, all contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The fibronectin domain of all three FLRTs can bind FGF receptors. This binding is thought to regulate FGF signaling during development. The LRR domains are responsible for both the localization of FLRTs in areas of cell contact and homotypic cell cell association. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting its involvement in the FGF signalling pathway.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-333)
Fournisseur:
ProSci Inc.
Description:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-332)
Fournisseur:
ProSci Inc.
Description:
Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-291)
Fournisseur:
ProSci Inc.
Description:
CD200 is a transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. It contains one Ig like V type domain and one Ig like C2 type domain in its extracelluar domain. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 and CD200R associate via their respective N-terminal Ig-like domains. In myeloid cells, CD200R initiates inhibitory signals following receptor-ligand contact. In T cells, CD200 functions as a co-stimulatory molecule independent of the CD28 pathway. In addition, CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-286)
Fournisseur:
ProSci Inc.
Description:
ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-284)
Fournisseur:
ProSci Inc.
Description:
C1QTNF1 is a secreted protein，contains 1 C1q domain and 1 collagen-like domain. C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher order molecular forms. C1QTNF1 is a novel adipokine, providing a significant framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. C1QTNF1 increases the production of aldosterone. C1QTNF1 is vastly expressed in obese subjects as well as up-regulated in hypertensive patients, C1QTNF1 is identified molecular link between obesity and hypertension. C1QTNF1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2411P)
Fournisseur:
ProSci Inc.
Description:
Smac peptide is used for blocking the activity of mSmac/DIABLO antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4475P)
Fournisseur:
ProSci Inc.
Description:
Slitrk5 peptide is used for blocking the activity of Slitrk5 antibody.
UOM:
1 * 50 µG
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