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Protéines et Peptides
Numéro de catalogue:
(PRSI4797P)
Fournisseur:
ProSci Inc.
Description:
KINDLIN3 peptide is used for blocking the activity of ACVR1C antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3489P)
Fournisseur:
ProSci Inc.
Description:
Raptor peptide is used for blocking the activity of the Raptor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3507P)
Fournisseur:
ProSci Inc.
Description:
TSC2 peptide is used for blocking the activity of the TSC2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2497P)
Fournisseur:
ProSci Inc.
Description:
IL-22 receptor peptide is used for blocking the activity of IL-22 receptor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3503P)
Fournisseur:
ProSci Inc.
Description:
TSC1 peptide is used for blocking the activity of the TSC1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-509)
Fournisseur:
ProSci Inc.
Description:
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-104)
Fournisseur:
ProSci Inc.
Description:
FGF-21 (Fibroblast growth factor 21) stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of betaKlotho.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-115)
Fournisseur:
ProSci Inc.
Description:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralisation. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-116)
Fournisseur:
ProSci Inc.
Description:
FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralisation. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3999P)
Fournisseur:
ProSci Inc.
Description:
TMP21 peptide is used for blocking the activity of TMP21 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1158P)
Fournisseur:
ProSci Inc.
Description:
DR3 peptide is used for blocking the activity of DR3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1159P)
Fournisseur:
ProSci Inc.
Description:
FLIP peptide is used for blocking the activity of FLIP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-608)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1), is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses. B7-H1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. PD-L1 is highly expressed in the heart, skeletal muscle, placenta and lung and weakly expressed in the thymus, spleen, kidney and liver. PD-L1 is expressed on activated T-cells, B-cells, dendritic cells, keratinocytes and monocytes. PD-L1 is up-regulated on T- and B-cells, dendritic cells, keratinocytes and monocytes after LPS and IFNG activation and up-regulated in B-cells activated by surface Ig cross-linking. PD-L1 involve in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-750)
Fournisseur:
ProSci Inc.
Description:
ERO1-Like Protein alpha (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1L acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. It associates with ERP44, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. ERO1L may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell. ERO1L responses to temperature stimulus, protein thiol-disulfide exchange, protein folding with or without chaperone cofactor and transport.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-779)
Fournisseur:
ProSci Inc.
Description:
Fms-Related Tyrosine Kinase 3 Ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). In synergy with other growth factors, Flt3 ligand stimulates the proliferation and differentiation of various blood cell progenitors by activiation of Flt 3 receptor.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-755)
Fournisseur:
ProSci Inc.
Description:
Secreted and Transmembrane Protein 1 (SECTM1) is a transmembrane and secreted protein that belongs to the SECTM family. SECTM1 is expressed in a perinuclear Golgi-like pattern. It is detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. SECTM1 is considered to participate in thymocyte signaling and the hematopoietic/immune system processes. It is reported that SECTM1 is a broadly expressed, IFN- gamma -inducible molecule, which functions as a potent costimulatory ligand for T cell activation and is synergistic with anti-CD28.
UOM:
1 * 50 µG
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